Mouse anti P53 (TP53 tumor suppressor protein), Primary Antibodies

• Catalog number
  MUB1501P
• Price
  Please ask
• Size
  100µg

• Host Source
  Mouse
• Clone Name
  DO-1
• Product Category
  Apoptosis,Cancer,Cell Cycle
• Species Reactivity
  Human
• Application
  ELISA,Flow cytometry,Immunoblotting,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (frozen),Immunohistochemistry (paraffin),Western blotting
• Immunogen
  DO-1 is a mouse monoclonal IgG2a antibody derived by fusion of mouse myeloma Sp2/0-Ag14 cells with spleen cells from BALB/c mice immunized with recombinant human wild type p53 protein expressed in E. coli.
• Purification Method
  NA
• Shipping Conditions
  NA
• Storage conditions
  Mouse anti P53 (TP53 tumor suppressor protein), Primary Antibodies t 4°C or for longer periods at -20°C in small aliquots.
• Datasheet link
  NA
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  P53   TP53   tumor   suppressor   protein   Primary   Antibodies  
• Gene symbol
  TP53
• Short name
  Mouse anti P53 (TP53 tumor suppressor protein), Primary Antibodies
• Technique
  Mouse, anti, antibody to, mouses
• Host
  mouse
• Isotype
  IgG2a/kappa
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to P53 (tumor protein p53 tumor suppressor protein), captor Antibodies
• Alternative technique
  murine, antibodies
• Alternative to gene target
  tumor protein p53, BCC7 and LFS1 and P53 and TRP53, TP53 and IDBG-26364 and ENSG00000141510 and 7157, MDM2/MDM4 family protein binding, nuclei, Trp53 and IDBG-191036 and ENSMUSG00000059552 and 22059, TP53 and IDBG-635147 and ENSBTAG00000001069 and 281542
• Tissue
  tumor

Gene info

• Identity
  HGNC:11998
• Gene
  TP53
• Long gene name
  tumor protein p53
• Synonyms
  • p53
  • LFS1
• Synonyms name
  • Li-Fraumeni syndrome
• GenBank acession
  • AF307851
• Locus
  17p13.1
• Discovery year
  1986-01-01
• Entrez gene record
  7157
• Pubmed identfication
  • 6396087
  • 3456488
  • 2047879
• RefSeq identity
  • NM_000546
• VEGA ID
  OTTHUMG00000162125
• Locus Specific Databases
  • IARC TP53 Mutation Database
  • p53 UMD TP53 mutation database
  • Database of Germline p53 Mutations
  • MUTP53LOAD, Mutant p53 Loss Of Activity Database
  • LRG_321

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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