anti- CXCL8/IL8 antibody

• Catalog number
  FNab02098
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Protein A+G purification
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.
• Immunogen
  interleukin 8
• Synonyms
  C X C motif chemokine 8, CXC chemokine ligand 8, CXCL 8, CXCL8, IL 8, IL8, Inteleukin 8, interleukin 8
• Calculated MW
  11 kDa
• Uniprot ID
  P10145
• Specificity
  Human, Mouse
• Tested Application
  ELISA, IHC, WB
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
• Image1
  Recombinant protein were subjected to SDS PAGE followed by western blot with FNab02098 at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Gene
  Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. Endothelial cells store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 proteins encoded by the IL8 gene. IL-8 is initially produced as a precursor peptide of 99 amino acids long which then undergoes cleavage to create several active IL-8 isoforms. In culture, a 72 amino acid peptide is the major form secreted by macrophages. Recombinant, rec. E. coli interleukin-8 for cell culture or antibody production.
• French translation
  anticorps

• Gene target
  CXCL8/IL8  
• Gene symbol
  CXCL8
• Short name
  anti- CXCL8/IL8 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Mouse
• Isotype
  IgG1
• Alternative name
  antibody to- CXCL8/interleukin 8 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  interleukin 8, GCP-1 and GCP1 and IL8 and LECT and LUCT and LYNAP and MDNCF and MONAP and NAF and NAP-1 and NAP1, IL8 and IDBG-23954 and ENSG00000169429 and 3576, chemokine activity, Extracellular, IL8 and IDBG-643010 and ENSBTAG00000019716 and 280828

Gene info

• Identity
  HGNC:6025
• Gene
  CXCL8
• Long gene name
  C-X-C motif chemokine ligand 8
• Synonyms gene
  • IL8
• Synonyms gene name
  • interleukin 8
  • chemokine (C-X-C motif) ligand 8
• Synonyms
  • SCYB8
  • LUCT
  • LECT
  • MDNCF
  • TSG-1
  • IL-8
  • NAP-1
  • 3-10C
  • MONAP
  • AMCF-I
  • LYNAP
  • NAF
  • b-ENAP
  • GCP-1
  • K60
  • GCP1
  • NAP1
• Synonyms name
  • neutrophil-activating peptide 1
  • granulocyte chemotactic protein 1
  • monocyte-derived neutrophil chemotactic factor
  • lung giant cell carcinoma-derived chemotactic protein
  • tumor necrosis factor-induced gene 1
  • monocyte-derived neutrophil-activating peptide
  • lymphocyte derived neutrophil activating peptide
  • beta endothelial cell-derived neutrophil activating peptide
  • alveolar macrophage chemotactic factor I
• GenBank acession
  • Y00787
• Locus
  4q13.3
• Discovery year
  1989-06-30
• Entrez gene record
  3576
• Pubmed identfication
  • 1427896
  • 11178128
• RefSeq identity
  • NM_000584
• Classification
  • Chemokine ligands
  • Interleukins
• VEGA ID
  OTTHUMG00000151316

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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