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Rabbit Anti Human CXCL8 Antibody-Non-conjugated

  • Catalog number
    CSB-PA08329A0Rb_100ug
  • Product name
    Rabbit Anti Human CXCL8 Antibody-Non-conjugated
  • Size
    100ug
  • Long name
    Rabbit Antibody against Human CXCL8, Non-conjugated
  • Short name
    Anti-CXCL8
  • Synonym name
    CXCL8 Human Antibody
  • Host
    Rabbit, Rabbits
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA,IF;Recommended dilution:IF:1:50-1:200
  • Conjugation
    Non-conjugated
  • Antibody isotype
    IgG
  • UniProt ID
    P10145
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Purity
    >95%
  • Purification method
    Protein G purified
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant Human Interleukin-8 protein (28-99AA)
  • Immunogen species
    Human
  • Alias
    CXCL8,IL8,Interleukin-8
  • Background
    Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1, TARC and also for the malaria parasites P.vivax and P.knowlesi. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels.
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    CXCL8 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Short name of the antigen
    Interleukin-8
  • Gene target
    CXCL8 Non-conjugated
    • Gene info
  • Gene symbol
    CXCL8
  • technique filter
    • anti human
    • Antibody
    • Rabbit
    • anti
  • Technique
    anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
  • Alternative technique
    antibodies, rabbit-anti