RAT ANTI MOUSE DECTIN-2:FITC Antibody

• Catalog number
  GEN210975
• Price
  Please ask
• Size
  100ug

• Also known as
  DECTIN-2
• Other names
  C-type lectin domain family 6 member A isoform 3; C-type lectin domain family 6 member A; C-type lectin domain family 6 member A; dectin-2; DC-associated C-type lectin 2; natural killer complex lectin; C-type lectin superfamily member 10; dendritic cell-associated C-type lectin 2; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10; C-type lectin domain family 4, member n; C-type lectin superfamily member 10; Dendritic cell-associated C-type lectin 2
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  Clec4n; Clec6a; Nkcl; Clec6a; Clecsf10; Clec4n; Clecsf10; Dectin2; DC-associated C-type lectin 2; Dectin-2
• Gene name synonims
  Clec4n; Clec6a; Nkcl; Clec6a; Clecsf10; Clec4n; Clecsf10; Dectin2; DC-associated C-type lectin 2; Dectin-2
• Other gene names
  Clec4n; Clec6a; Nkcl; Clec6a; Clecsf10; Clec4n; Clecsf10; Dectin2; DC-associated C-type lectin 2; Dectin-2
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a
• Clone
  D2.11E4
• Host organism
  Rat (Rattus norvegicus)
• Species reactivity
  Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  DECTIN-2 This item recognises mouse DC-associated C-type lectin-2 (Dectin-2), a type II transmembrane protein that is a member of the C-type lectin superfamily. In mouse, dectin-2 is predominantly expressed on tissue macrophages and some dendritic cells. Clone D2.11E4 does not stain brain microglia or meningeal macrophages. _x000D__x000D_Significant expression of Dectin-2 has been reported on macrophages in the red pulp and marginal zones of the spleen, kupffer cells in the liver and alveolar macrophages in the lung. Peripheral blood monocytes express low levels of dectin-2 but transient up-regulation of expression has been demonstrated on monocytes at sites of inflammation. _x000D__x000D__x000D_The function of dectin-2 has not been fully determined but studies suggest a possible role in immune-surveillance.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  FITC (Purified IgG - liquid)
• Concentration
  IgG concentration 0.1 miligram per 1 mililiter
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term. the antibody should be stored undiluted. Storage in frost-free freezers is not recommended. the antibody is photosensitive and should be protected from light. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
• Tested applications
  Flow Cytometry (FACS)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. This is against a protein of mus musculus directed antibody.
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This MBS Monoclonals Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MBS Monoclonals FITC is highly sensitive to pH extremes.
• Conjugation
  Anti-FITC Antibody
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus, Rattus norvegicus
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• French translation
  anticorps

• Gene target
  DECTIN-2  
• Gene symbol
  CLEC6A, CLEC4D, CLEC7A, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2, KRTAP13-2
• Short name
  ANTI MOUSE DECTIN-2:FITC Antibody
• Technique
  anti mouse, Antibody, Mouse, anti, FITC, antibody to, anti mouse antibodies, antibodies against human proteins, antibodies for, Fluorescein, mouses
• Host
  Rat
• Label
  FITC
• Species
  Mouse, Mouses, Rats
• Alternative name
  Anti-RAT ANTI MOUSE DECTIN-2:FITC
• Alternative technique
  antibodies, murine, fluorescine

Gene info

• Identity
  HGNC:14556
• Gene
  CLEC6A
• Long gene name
  C-type lectin domain containing 6A
• Synonyms gene
  • CLECSF10
• Synonyms gene name
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10
  • C-type lectin domain family 6, member A
  • C-type lectin domain family 6 member A
• Synonyms
  • dectin-2
  • hDECTIN-2
• GenBank acession
  • AY321309
• Locus
  12p13.31
• Discovery year
  2004-11-18
• Entrez gene record
  93978
• RefSeq identity
  • NM_001007033
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000168672

Gene info

• Identity
  HGNC:14554
• Gene
  CLEC4D
• Long gene name
  C-type lectin domain family 4 member D
• Synonyms gene
  • CLECSF8
• Synonyms gene name
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8
  • C-type lectin domain family 4, member D
• Synonyms
  • Mpcl
  • CD368
  • MCL
  • Dectin-3
• Synonyms name
  • Dectin 3
• GenBank acession
  • AF411850
• Locus
  12p13.31
• Discovery year
  2004-10-20
• Entrez gene record
  338339
• RefSeq identity
  • NM_080387
• Classification
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000168674

Gene info

• Identity
  HGNC:14558
• Gene
  CLEC7A
• Long gene name
  C-type lectin domain containing 7A
• Synonyms gene
  • CLECSF12
• Synonyms gene name
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12
  • C-type lectin domain family 7, member A
  • C-type lectin domain family 7 member A
• Synonyms
  • DECTIN-1
  • hDectin-1
  • CD369
  • SCARE2
• GenBank acession
  • AY009090
• Locus
  12p13.2
• Discovery year
  2001-02-01
• Entrez gene record
  64581
• RefSeq identity
  • NM_197954
• Classification
  • C-type lectin domain containing
  • CD molecules
  • Scavenger receptors
• VEGA ID
  OTTHUMG00000133597
• Locus Specific Databases
  • LRG_179

Gene info

• Identity
  HGNC:31639
• Gene
  MIR7-2
• Long gene name
  microRNA 7-2
• Synonyms gene
  • MIRN7-2
• Synonyms
  • hsa-mir-7-2
• Locus
  15q26.1
• Discovery year
  2004-04-23
• Entrez gene record
  407044
• RefSeq identity
  • NR_029606
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:32051
• Gene
  MIR329-2
• Long gene name
  microRNA 329-2
• Synonyms gene
  • MIRN329-2
• Synonyms
  • hsa-mir-329-2
• Locus
  14q32.31
• Discovery year
  2005-07-11
• Entrez gene record
  574409
• RefSeq identity
  • NR_029968
• Classification
  • MicroRNA MIR329 family

Gene info

• Identity
  HGNC:32091
• Gene
  MIR512-2
• Long gene name
  microRNA 512-2
• Synonyms gene
  • MIRN512-2
• Synonyms
  • hsa-mir-512-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574459
• RefSeq identity
  • NR_030181
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

Gene info

• Identity
  HGNC:35282
• Gene
  MIR1289-2
• Long gene name
  microRNA 1289-2
• Synonyms gene
  • MIRN1289-2
• Synonyms
  • hsa-mir-1289-2
• Locus
  5q31.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302134
• RefSeq identity
  • NR_031621
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:33641
• Gene
  MIR509-2
• Long gene name
  microRNA 509-2
• Synonyms gene
  • MIRN509-2
• Synonyms
  • hsa-mir-509-2
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126301
• RefSeq identity
  • NR_030586
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:18923
• Gene
  KRTAP13-2
• Long gene name
  keratin associated protein 13-2
• Synonyms
  • KAP13-2
• GenBank acession
  • AP001708
• Locus
  21q22.11
• Discovery year
  2003-02-21
• Entrez gene record
  337959
• Pubmed identfication
  • 12359730
• Classification
  • Keratin associated proteins
• VEGA ID
  OTTHUMG00000057793

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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