TLR8 (TAntibody (Clone 44B05)
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Catalog number
3558-100
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Price
Please ask
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Size
100 µl
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Antibody Target
TLR8
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Target Alternative Name
LR8 , Anti-TLR8 , CD288 , CD 288 , mgC119599 , # mgC119600
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Antibody Type
Monoclonal
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Clone
44B05
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Species Reactivities
Human
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Immunogen Sequence
Recombinant human TLR8
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Accession
NP_619542
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Gene Id
51311
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Appearance
Colorless liquid
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Form
Liquid
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Concentration
1.0 mg/ml
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Formulation
100 µl (1 mg/ml) Protein G purified mouse anti-TLR8 monoclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
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Purification
Affinity purified
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Application
Western blot, Flow cytometry
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Application And Usages
Western blotting (1:200-1000 dilutions) and FACS analysis. Ramos cell lysate can be used as a positive control and a 120 kDa band is detected in Western blotting. For FACS analysis, we recommend 1-4 ml per million cells. However, the optimal conditions should be determined individually.
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Description
The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1 contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and sμggests that these receptors are involved in mediating inflammatory responses. TLR6 is highly homologous to TLR1, and like other members of TLR family, it induces NFkB signaling upon activation. TLR8 gene contains three exons, two of which have coding function. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes.
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Storage Condition
-20 °C
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Shipping Condition
gel pack
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Shelf Life
12 months
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Usage
For Research Use Only! Not to be used in humans.
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Handling
The antibody solution should be gently mixed before use.
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Western Blot Verified
Verified
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Immunocytochemistry Verified
Not Verified
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Immunofluorescence Verified
Not Verified
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Immunoprecipitation Verified
Not Verified
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ELISA Verified
Not Verified
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ChIP Verified
Not Verified
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Flow Cytometry Verified
Not Verified
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Gene target
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Gene symbol
TLR8-AS1, TLR8
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Short name
TLR8 (TAntibody (Clone 44B05)
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Isotype
Mouse IgG1
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Alternative name
toll-like receptor 8 (TAntibody (clonality 44B05)
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Alternative to gene target
toll-like receptor 8, TLR8 and IDBG-44288 and ENSG00000101916 and 51311, drug binding, Plasma membranes, Tlr8 and IDBG-185523 and ENSMUSG00000040522 and 170744
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Clone name
44B05
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Gene info
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Identity
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Gene
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Long gene name
TLR8 antisense RNA 1
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Synonyms gene name
- TLR8 antisense RNA 1 (non-protein coding)
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Locus
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Discovery year
2011-07-29
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Entrez gene record
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
toll like receptor 8
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-04-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Toll like receptors
- CD molecules
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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