p21,WAF1 (Cip1, Sdi1, Pic1,Wild-type p53-activated Fragment, Tumor Suppressor Protein)
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Catalog number
GEN602630
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Price
Please ask
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Size
500ul
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Also known as
p21,WAF1
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Other names
p21; Cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1; p21; CDK-interacting protein 1; melanoma differentiation-associated protein; cyclin-dependent kinase inhibitor 1A (P21); CDK-interacting protein 1; Melanoma differentiation-associated protein; p21
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
Cdkn1a; Cdkn1a; P21; CDKI; CIP1; SDI1; Waf1; mda6; CAP20; Cdkn1; p21WAF; p21Cip1; Cip1; Waf1
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Gene name synonims
Cdkn1a; Cdkn1a; P21; CDKI; CIP1; SDI1; Waf1; mda6; CAP20; Cdkn1; p21WAF; p21Cip1; Cip1; Waf1
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Other gene names
Cdkn1a; Cdkn1a; P21; CDKI; CIP1; SDI1; Waf1; mda6; CAP20; Cdkn1; p21WAF; p21Cip1; Cip1; Waf1
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG2a
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Clone
0.N.488
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Host organism
Mouse (Mus musculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes human p21WAF1/Cip1/Sdi1/Pic1 tumor suppressor protein. Does not react with mouse and rat; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Affinity Purified by Protein A affinity chromatography.
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Form Appearance
Supplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 15mM sodium azide. Also supplied without BSA and sodium azide. See P1000-54X.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add glycerol (40-50%) and aliquot. Freeze the antibody should be stored at -20 degrees Celsius.. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
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Tested applications
Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF)
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Description
Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
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Gene target
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Gene symbol
CDKN1A
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Short name
p21 WAF1 (Cip1, Sdi1, Pic1 Wild- p53-activated , Tumor Suppressor Protein)
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Isotype
Antibody fragments and scFv fragments, single chain variable fragments can be E. coli expressed. Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small. IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion. Complement fragments, bp DNA fragments are common.
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Alternative name
Anti-p21,WAF1 (Cip1, Sdi1, Pic1,Wild-type p53-activated Fragment, Tumor Suppressor Protein)
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Tissue
tumor
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Gene info
MeSH Data
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Name
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Concept
Scope note:
A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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