WAF1, p21 (Wild-type p53-activated Fragment, Cip1, Sdi1, Pic1 Tumor Suppressor Protein)

• Catalog number
  MBS601175
• Price
  Please ask
• Size
  5x0.2 mg

• Products_type
  Antibody
• Products_short_name
  [WAF1, p21]
• Products_name_syn
  [Anti -WAF1, p21 (Wild-type p53-activated Fragment, Cip1, Sdi1, Pic1 Tumor Suppressor Protein)]
• Clonality
  Monoclonal
• Clone
  [0.T.180/0.T.180A]
• Reactivity
  Human, Mouse
• Specificity
  Recognizes WAF1, p21,~ 21kD. Species crossreactivity: mouse.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as liquid in 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% sodium azide.
• Storage_stability
  -20 degree C
• Tested_application
  Western Blot (WB), Immunoprecipitation (IP)
• Description
  Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.

• Gene target
  WAF1   p21   Wild   p53-activated   Cip1   Sdi1   Pic1   Tumor   Suppressor   Protein  
• Gene symbol
  CDKN1A
• Short name
  WAF1, p21 (Wild- p53-activated , Cip1, Sdi1, Pic1 Tumor Suppressor Protein)
• Host
  Mouse
• Isotype
  IgG1,k+2b,k, Antibody fragments and scFv fragments, single chain variable fragments can be E. coli expressed. Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small. IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion. Complement fragments, bp DNA fragments are common.
• Alternative name
  WAF1, p21 (Wild-classification p53-activated Fragment, Cip1, Sdi1, Pic1 Tumor Suppressor Protein)
• Tissue
  tumor

Gene info

• Identity
  HGNC:1784
• Gene
  CDKN1A
• Long gene name
  cyclin dependent kinase inhibitor 1A
• Synonyms gene
  • CDKN1
• Synonyms gene name
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1)
• Synonyms
  • P21
  • CIP1
  • WAF1
  • SDI1
  • CAP20
  • p21CIP1
  • p21Cip1/Waf1
  • p21
• GenBank acession
  • U03106
• Locus
  6p21.2
• Discovery year
  1994-05-24
• Entrez gene record
  1026
• RefSeq identity
  • NM_078467
• VEGA ID
  OTTHUMG00000014603

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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