UF 010
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Catalog numberB1146-50
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PricePlease ask
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Size50 mg
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Alternative_name4-Bromo-N'-butylbenzohydrazide
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DescriptionUF 010 is class I HDAC inhibitor that displays >6- fold selectivity over other HDACs. It has an IC₅₀ value of 0.06, 0.1, and 1.5 μM for HDACs 3, 2, 1 and 8 respectively. In vitro experimental data shows accumulation of acetylated histones in HCT116 cells. UF 010 is known to arrest cells at G1/S transition inhibiting proliferation of various cancer cell lines.
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CAS Number537672-41-6
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₁H₁₅BrN₂O
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Molecular Weight271.15
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO(>25 mg/ml)
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HandlingProtect from air and light
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Tag LineUF 010 is potent and selective class I HDAC inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID4596836
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SMILESCCCCNNC(=O)C1=CC=C(C=C1)Br
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InChi1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15)
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InChi KeyBVQCFCYPFJOOAV-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameUF 010
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Alternative nameUF 010
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