UF 010

  • Catalog number
    B1146-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    4-Bromo-N'-butylbenzohydrazide
  • Description
    UF 010 is class I HDAC inhibitor that displays >6- fold selectivity over other HDACs. It has an IC₅₀ value of 0.06, 0.1, and 1.5 μM for HDACs 3, 2, 1 and 8 respectively. In vitro experimental data shows accumulation of acetylated histones in HCT116 cells. UF 010 is known to arrest cells at G1/S transition inhibiting proliferation of various cancer cell lines.
  • CAS Number
    537672-41-6
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₁H₁₅BrN₂O
  • Molecular Weight
    271.15
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO(>25 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    UF 010 is potent and selective class I HDAC inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    4596836
  • SMILES
    CCCCNNC(=O)C1=CC=C(C=C1)Br
  • InChi
    1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15)
  • InChi Key
    BVQCFCYPFJOOAV-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
    010  
  • Short name
    UF 010
  • Alternative name
    UF 010
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