GW788388

• Catalog number
  2820-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  4-[4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl]-2-pyridinyl]-N-(tetrahydro-2H-pyran-4-yl)-benzamide
• Description
  GW788388 is a potent and selective inhibitor of transforming growth factor beta receptor I (TGF-βR1) (activin receptor-like kinase 5, ALK5) (IC₅₀ = 18 nM). Also inhibits TGF-β type II receptor and activin type II receptor activities, but does not inhibit BMP type II receptor.
• CAS Number
  452342-67-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₅H₂₃N₅O₂
• Molecular Weight
  425.48
• Cell Permeable
  yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>40 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent and selective transforming growth factor beta receptor I (TGF-βR1) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD20527321
• PubChem CID
  10202642
• PubChem CID Link
• SMILES
  C1COCCC1NC(=O)C2=CC=C(C=C2)C3=NC=CC(=C3)C4=C(NN=C4)C5=CC=CC=N5
• InChi
  InChI=1S/C25H23N5O2/c31-25(29-20-9-13-32-14-10-20)18-6-4-17(5-7-18)23-15-19(8-12-27-23)21-16-28-30-24(21)22-3-1-2-11-26-22/h1-8,11-12,15-16,20H,9-10,13-14H2,(H,28,30)(H,29,31)
• InChi Key
  SAGZIBJAQGBRQA-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  GW788388  
• Short name
  GW788388
• Alternative name
  GW788388

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