Mouse Monoclonal [clone 8E3] (IgG2a,k) to Human PTPRN / IA-2

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Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus

Gene target

Monoclonal 8E3] IgG2a PTPRN IA-2
Gene symbol

PTPRN, RRN3, INSM1, INSM2, PTPRN2, MIR1289-2, MIR521-2, MIR509-2, MIR512-2, MIR7-2
Short name

Mouse Monoclonal [clone 8E3] (IgG2a k) PTPRN / IA-2
Technique

Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
Host

mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
Isotype

IgG2a
Species

Human, Humans, Mouses
Alternative name

Mouse monoclonal [clonality 8E3] (IgG2a,k) to H. sapiens protein tyrosine phosphatase, receptor classification, N / IA-2
Alternative technique

murine
Alternative to gene target

protein tyrosine phosphatase, receptor type, N, IA-2 and IA-2/PTP and IA2 and ICA512 and R-PTP-N, PTPRN and IDBG-81527 and ENSG00000054356 and 5798, GTPase binding, Plasma membranes, Ptprn and IDBG-170581 and ENSMUSG00000026204 and 19275, PTPRN and IDBG-643992 and ENSBTAG00000013798 and 286810
Clone name

8E3

Identity

HGNC:9676
Gene

PTPRN
Long gene name

protein tyrosine phosphatase receptor type N
Synonyms
- IA-2
- ICA512
Synonyms name
- insulinoma-associated tyrosine-phosphatase-like protein
- islet cell antigen 512
Locus

2q35
Discovery year

1995-02-17
Entrez gene record

5798
Pubmed identfication
- 8024693
Classification
- Protein tyrosine phosphatases receptor type
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000133129

Identity

HGNC:30346
Gene

RRN3
Long gene name

RRN3 homolog, RNA polymerase I transcription factor
Synonyms gene name
- RRN3 RNA polymerase I transcription factor homolog (yeast)
- RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
Synonyms
- DKFZp566E104
- TIF-IA
Synonyms name
- transcription initiation factor IA
GenBank acession
- AF227156
Locus

16p13.11
Discovery year

2004-08-19
Entrez gene record

54700
Pubmed identfication
- 10758157
- 11250903
RefSeq identity
- NM_018427
Classification
- Armadillo like helical domain containing
VEGA ID

OTTHUMG00000129847

Identity

HGNC:9677
Gene

PTPRN2
Long gene name

protein tyrosine phosphatase receptor type N2
Synonyms gene name
- protein tyrosine phosphatase, receptor type, N polypeptide 2
Synonyms
- KIAA0387
- phogrin
- ICAAR
- IA-2beta
Synonyms name
- IAR PTPRP
GenBank acession
- AB002385
Locus

7q36.3
Discovery year

1998-03-23
Entrez gene record

5799
Pubmed identfication
- 8954911
- 9220540
Classification
- MicroRNA protein coding host genes
- Protein tyrosine phosphatases receptor type
VEGA ID

OTTHUMG00000152646