100ug-Anti-Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL)

• Catalog number
  PAA139Mu01-100ug
• Price
  Please ask
• Size
  100ug

• Organism Species
  Mus musculus (Mouse)
• Source
  Polyclonal antibody preparation
• Purification
  Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Buffer Formulation
  PBS, pH7.4,containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Item Name
  Tumor Necrosis Factor Related Apoptosis Inducing Ligand
• Immunogen
  RPA139Mu01-Recombinant Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL)
• Image number
  3
• Species reactivity
  Human,Mouse
• Sequence of immunogen
  TRAIL (Met40~Asn291)
• Aplication
  WB,IHC
• Clonality
  Rabbit polyclonal
• Concentration
  500ug/ml
• Alternative Names
  CD253; TNFSF10; APO2L; Apo2-L; TL2; TRAIL; Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand
• Applicable Secondary Antibody
  SAA544Rb59, SAA544Rb58, SAA544Rb57, SAA544Rb18, SAA544Rb19
• Manual link
• Delivery condition
  4℃ with ice bags
• Storage instructions
  Avoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. This 1 is suited for programmed cell-death studies. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.

• Gene target
  100ug   Tumor   Necrosis   Factor   Related   Ligand   TRAIL  
• Gene symbol
  TNFSF10, TNFRSF10B
• Short name
  100ug-Anti-Tumor Necrosis Factor Apoptosis Ligand (TRAIL)
• Technique
  apoptosis, anti-, anti, antibody to, antibodies, apoptosis pathway
• Host
  Rabbit
• Alternative name
  100ug-Antibody toTumor Necrosis Factor Related programmed cellular destruction Inducing Ligand (TRAIL)
• Alternative technique
  celldeath, antibodies
• Tissue
  tumor

Gene info

• Identity
  HGNC:11925
• Gene
  TNFSF10
• Long gene name
  TNF superfamily member 10
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 10
• Synonyms
  • TRAIL
  • Apo-2L
  • TL2
  • CD253
• GenBank acession
  • U37518
• Locus
  3q26
• Discovery year
  1998-12-04
• Pubmed identfication
  • 8777713
  • 8663110
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000156917

Gene info

• Identity
  HGNC:11905
• Gene
  TNFRSF10B
• Long gene name
  TNF receptor superfamily member 10b
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 10b
• Synonyms
  • DR5
  • KILLER
  • TRICK2A
  • TRAIL-R2
  • TRICKB
  • CD262
  • TRAILR2
• GenBank acession
  • AF012628
• Locus
  8p21.3
• Discovery year
  1998-12-04
• Entrez gene record
  8795
• Pubmed identfication
  • 9285725
  • 9311998
• RefSeq identity
  • NM_147187
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000097826

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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