anti- HAX1 antibody

• Catalog number
  FNab03765
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
• Immunogen
  HCLS1 associated protein X-1
• Synonyms
  FLJ17042, FLJ18492, FLJ93803, HAX 1, HAX1, HCLS1 associated protein X 1, HCLSBP1, HS1 associating protein X 1, HS1 binding protein 1, HS1BP1, HSP1BP 1, SCN3
• Calculated MW
  36 kDa
• Uniprot ID
  O00165
• Specificity
  Human, Mouse
• Tested Application
  ELISA, WB, IHC, IF
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
• Image1
  Immunohistochemistry of paraffin-embedded human lymphoma using FNab03765(HAX1 antibody) at dilution of 1:50
• Image4
  HeLa cells were subjected to SDS PAGE followed by western blot with FNab03765( HAX1 Antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HAX1  
• Gene symbol
  HAX1
• Short name
  anti- HAX1 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- HCLS1 associated protein X-1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  HCLS1 associated protein X-1, HCLSBP1 and HS1BP1 and SCN3, HAX1 and IDBG-102924 and ENSG00000143575 and 10456, protein N-terminus binding, nuclei, Hax1 and IDBG-165357 and ENSMUSG00000027944 and 23897, HAX1 and IDBG-632533 and ENSBTAG00000013025 and 506895

Gene info

• Identity
  HGNC:16915
• Gene
  HAX1
• Long gene name
  HCLS1 associated protein X-1
• Synonyms
  • HS1BP1
  • HCLSBP1
  • HAX-1
• Synonyms name
  • HCLS1 (and PKD2) associated protein
• GenBank acession
  • U68566
• Locus
  1q21.3
• Discovery year
  2005-05-19
• Entrez gene record
  10456
• Pubmed identfication
  • 9058808
  • 10760273
• RefSeq identity
  • NM_006118
• VEGA ID
  OTTHUMG00000035978
• Locus Specific Databases
  • HAX1base: Mutation registry for severe congenital neutropenia (Kostmann disease)
  • LRG_64

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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