Anti-ICK Antibody

• Catalog number
  A1172-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  ICK
• Target Alternative Name
  KIAA0936, Serine/threonine-protein kinase ICK, Intestinal cell kinase, hICK, Laryngeal cancer kinase 2, LCK2, MAK-related kinase, MRK
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ICK
• Accession
  Q9UPZ9
• Gene Id
  22858
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
• Purification
  Affinity purified
• Application
  WB, IH, IF/IC
• Positive Control
  WB: HeLa, HEL293 cell lysates; IHC: human brain tissue; IFC: HEK293T cells
• Application And Usages
  WB; 1:500 – 1:2000, IHC; 1:50 – 1:200, IF/IC; 1:50 – 1:100
• Description
  Required for ciliogenesis. Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length. Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity). Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ICK  
• Gene symbol
  CILK1
• Short name
  Anti-ICK Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toICK (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  intestinal cell (MAK-like) kinase, ECO and LCK2 and MRK, ICK and IDBG-90915 and ENSG00000112144 and 22858, transferase activity, nuclei, Ick and IDBG-186294 and ENSMUSG00000009828 and 56542, ICK and IDBG-632721 and ENSBTAG00000015590 and 506286

Gene info

• Identity
  HGNC:21219
• Gene
  CILK1
• Long gene name
  ciliogenesis associated kinase 1
• Synonyms gene
  • ICK
• Synonyms gene name
  • intestinal cell (MAK-like) kinase
  • intestinal cell kinase
• Synonyms
  • MRK
  • LCK2
  • KIAA0936
  • MGC46090
• Synonyms name
  • serine/threonine-protein kinase ICK
  • MAK-related kinase
• GenBank acession
  • AB023153
• Locus
  6p12.1
• Discovery year
  2003-08-21
• Entrez gene record
  22858
• Pubmed identfication
  • 12103360
• RefSeq identity
  • NM_016513
• VEGA ID
  OTTHUMG00000014870

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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