Rabbit Anti Human ICK Antibody-Non-conjugated

• Catalog number
  CSB-PA891800LA01HU_100ug
• Price
  Please ask
• Size
  100ug

• Long name
  Rabbit Antibody against Human ICK, Non-conjugated
• Synonym name
  ICK Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA,WB,IHC;Recommended dilution:WB:1:500-5000,IHC:1:20-1:200
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  Q9UPZ9
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant Human Serine/threonine-protein kinase ICK protein (150-275AA)
• Immunogen species
  Human
• Alias
  Serine/threonine-protein kinase ICK,Intestinal cell kinase,hICK,Laryngeal cancer kinase 2,LCK2,MAK-related kinase,MRK,ICK,KIAA0936
• Background
  Required for ciliogenesis (PubMed:24797473). Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length (PubMed:24853502). Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity). Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity).
• Clonality
  Polyclonal antibody
• Shipping and storage
  ICK Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Short name of the antigen
  Serine/threonine-protein kinase ICK
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  ICK   Non-conjugated  
• Gene symbol
  CILK1
• Short name
  Anti-ICK
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  ICK Antibody
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  intestinal cell (MAK-like) kinase, ECO and LCK2 and MRK, ICK and IDBG-90915 and ENSG00000112144 and 22858, transferase activity, nuclei, Ick and IDBG-186294 and ENSMUSG00000009828 and 56542, ICK and IDBG-632721 and ENSBTAG00000015590 and 506286

Gene info

• Identity
  HGNC:21219
• Gene
  CILK1
• Long gene name
  ciliogenesis associated kinase 1
• Synonyms gene
  • ICK
• Synonyms gene name
  • intestinal cell (MAK-like) kinase
  • intestinal cell kinase
• Synonyms
  • MRK
  • LCK2
  • KIAA0936
  • MGC46090
• Synonyms name
  • serine/threonine-protein kinase ICK
  • MAK-related kinase
• GenBank acession
  • AB023153
• Locus
  6p12.1
• Discovery year
  2003-08-21
• Entrez gene record
  22858
• Pubmed identfication
  • 12103360
• RefSeq identity
  • NM_016513
• VEGA ID
  OTTHUMG00000014870

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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