Human Neutrophil Elastase, Lyophilized

• Catalog number
  MI-HNE-L-B
• Price
  Please ask
• Size
  1 mg

• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  The term “freeze-dry” is a lay description for the process of lyophilization protein powder. It is the conversion of water from a frozen state to a gaseous state without going through a liquid state. Aliquoting with 25 mM HEPES-KOH, pH 7.2 and 1 mM DTT and 10% weight on volume glycerol is suitable for storage of the reconstituted powder. The freeze-dry process removes moisture from the cells of specimens while the specimens remain frozen.

• Gene target
  Neutrophil   Elastase  
• Gene symbol
  ELANE, SERPINB1
• Short name
  Neutrophil Elastase,
• Species
  Human, Humans
• Alternative name
  H. sapiens Neutrophil Elastase, Lyophilized

Gene info

• Identity
  HGNC:3309
• Gene
  ELANE
• Long gene name
  elastase, neutrophil expressed
• Synonyms gene
  • ELA2
• Synonyms gene name
  • elastase 2, neutrophil
• Synonyms
  • NE
  • HNE
  • HLE
  • PMN-E
• Synonyms name
  • neutrophil elastase
  • leukocyte elastase
  • medullasin
  • PMN Elastase
  • polymorphonuclear leukocyte elastase
• Locus
  19p13.3
• Discovery year
  1989-09-08
• Entrez gene record
  1991
• Pubmed identfication
  • 2902087
• RefSeq identity
  • NM_001972
• Classification
  • Granule associated serine proteases of immune defence
  • Complement system regulators and receptors
• VEGA ID
  OTTHUMG00000181839
• Locus Specific Databases
  • ELA2base: Mutation registry for Cyclic and congenital neutropenia
  • LRG_57

Gene info

• Identity
  HGNC:3311
• Gene
  SERPINB1
• Long gene name
  serpin family B member 1
• Synonyms gene
  • ELANH2
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1
  • serpin peptidase inhibitor, clade B (ovalbumin), member 1
• Synonyms
  • EI
  • PI2
  • LEI
  • MNEI
• Synonyms name
  • leukocyte elastase inhibitor
  • monocyte/neutrophil elastase inhibitor
  • anti-elastase
• GenBank acession
  • M93056
• Locus
  6p25.2
• Discovery year
  1993-07-27
• Entrez gene record
  1992
• Pubmed identfication
  • 1376927
  • 24172014
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000014124

MeSH Data

• Name
  Freeze Drying
• Concept
  Scope note: Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products.
• Tree numbers
  • E01.370.225.500.620.760.160.260
  • E01.370.225.750.600.760.160.260
  • E02.792.156.260
  • E05.200.500.620.760.160.260
  • E05.200.750.600.760.160.260
  • E05.760.156.260
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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