Human Neutrophil Elastase

• Catalog number
  MBS318184
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Native Protein
• Products_short_name
  [Elastase]
• Other_names
  [elastase; Elastase]
• Purity
  >95% pure (SDS-PAGE)
• Form
  Purified, LyophilizedReconstitute using 50mM Sodium Acetate, pH 5.5, containing 150mM Sodium chloride
• Concentration
  Activity: 20-22 units per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one umole of MeO-Suc-Ala-Ala-Pro-Val-pNA per minute at 25°C, in 100mM Tris-HCl, pH 7.5 with 500mM Sodium Chloride.
• Storage_stability
  Store at -20°C. Avoid multiple freeze/thaw cycles.
• Tested_application
  Specific methodologies have not been tested using this product.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  Neutrophil   Elastase  
• Gene symbol
  ELANE, SERPINB1
• Short name
  Neutrophil Elastase
• Species
  Human, Humans
• Alternative name
  H. sapiens Neutrophil Elastase

Gene info

• Identity
  HGNC:3309
• Gene
  ELANE
• Long gene name
  elastase, neutrophil expressed
• Synonyms gene
  • ELA2
• Synonyms gene name
  • elastase 2, neutrophil
• Synonyms
  • NE
  • HNE
  • HLE
  • PMN-E
• Synonyms name
  • neutrophil elastase
  • leukocyte elastase
  • medullasin
  • PMN Elastase
  • polymorphonuclear leukocyte elastase
• Locus
  19p13.3
• Discovery year
  1989-09-08
• Entrez gene record
  1991
• Pubmed identfication
  • 2902087
• RefSeq identity
  • NM_001972
• Classification
  • Granule associated serine proteases of immune defence
  • Complement system regulators and receptors
• VEGA ID
  OTTHUMG00000181839
• Locus Specific Databases
  • ELA2base: Mutation registry for Cyclic and congenital neutropenia
  • LRG_57

Gene info

• Identity
  HGNC:3311
• Gene
  SERPINB1
• Long gene name
  serpin family B member 1
• Synonyms gene
  • ELANH2
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1
  • serpin peptidase inhibitor, clade B (ovalbumin), member 1
• Synonyms
  • EI
  • PI2
  • LEI
  • MNEI
• Synonyms name
  • leukocyte elastase inhibitor
  • monocyte/neutrophil elastase inhibitor
  • anti-elastase
• GenBank acession
  • M93056
• Locus
  6p25.2
• Discovery year
  1993-07-27
• Entrez gene record
  1992
• Pubmed identfication
  • 1376927
  • 24172014
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000014124

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