Mouse Monoclonal [clone 12G5] (IgG2a) to Human CXCR4

Other size

please contact us to order other different size
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus

Gene target

Monoclonal 12G5] IgG2a CXCR4
Gene symbol

CXCR4
Short name

Mouse Monoclonal [clone 12G5] (IgG2a) CXCR4
Technique

Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
Host

mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
Isotype

IgG2a
Species

Human, Humans, Mouses
Alternative name

Mouse monoclonal [clonality 12G5] (IgG2a) to H. sapiens chemokine (C-X-C motif) receptor 4
Alternative technique

murine
Alternative to gene target

chemokine (C-X-C motif) receptor 4, CD184 and D2S201E and FB22 and HM89 and HSY3RR and LAP-3 and LAP3 and LCR1 and LESTR and NPY3R and NPYR and NPYRL and NPYY3R and WHIM, CXCR4 and IDBG-71032 and ENSG00000121966 and 7852, ubiquitin binding, Cell surfaces, Cxcr4 and IDBG-189999 and ENSMUSG00000045382 and 12767, CXCR4 and IDBG-642187 and ENSBTAG00000001060 and 281736
Clone name

12G5

Identity

HGNC:2561
Gene

CXCR4
Long gene name

C-X-C motif chemokine receptor 4
Synonyms gene name
- chemokine (C-X-C motif), receptor 4 (fusin)
- chemokine (C-X-C motif) receptor 4
Synonyms
- LESTR
- NPY3R
- HM89
- NPYY3R
- D2S201E
- fusin
- HSY3RR
- NPYR
- CD184
GenBank acession
- AF005058
Locus

2q22.1
Discovery year

1998-09-17
Entrez gene record

7852
Pubmed identfication
- 9599023
- 9379028
Classification
- C-X-C motif chemokine receptors
- CD molecules
VEGA ID

OTTHUMG00000153583
Locus Specific Databases
- CXCR4base: Mutation registry for WHIM syndrome (warts, hypogammaglobulinemia, immunodeficiency, and myelokathexis)
- LRG_51