MCM3 Antibody

• Catalog number
  F43448-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  MCM3
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the MCM3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This MCM3 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P25205
• Purity
  Antigen affinity
• Description
  The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq].
• Immunogen
  A portion of amino acids 36-64 from the human protein was used as the immunogen for this MCM3 antibody.
• Storage
  Aliquot the MCM3 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MCM3  
• Gene symbol
  MCM3
• Short name
  Anti-MCM3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to MCM3
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6945
• Gene
  MCM3
• Long gene name
  minichromosome maintenance complex component 3
• Synonyms gene name
  • minichromosome maintenance deficient (S. cerevisiae) 3
  • MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)
• GenBank acession
  • X62153
• Locus
  6p12.2
• Discovery year
  1994-12-13
• Entrez gene record
  4172
• Pubmed identfication
  • 1549468
• Classification
  • minichromosome maintenance 2-7 complex
  • MCM family
• VEGA ID
  OTTHUMG00000014844

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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