IP3 Receptor Antibody, ALEXA FLUOR 647
-
Catalog numberbs-8869R-A647
-
PricePlease ask
-
Size100ul
-
-
Long nameIP3 Receptor Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
-
Also known asAnti-IP3 Receptor PAb ALEXA FLUOR 647
-
CategoryConjugated Primary Antibodies
-
Conjugated withALEXA FLUOR® 647
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenIP3 Receptor
-
SpecificityThis is a highly specific antibody against IP3 Receptor.
-
ModificationUnmodified
-
Modification SiteNone
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
Immunogen range110-160/2758
-
Subcellular locationCytoplasm
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IP3 Receptor
-
Gene ID Number3708
-
Swiss ProtQ14643
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigenIntracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
-
PurificationPurified by Protein A.
-
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission650nm/665nm
-
SynonymsACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94; Inositol 1,4,5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor; ITPR1
-
PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-IP3 Receptor exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugationAlexa Fluor, ALEXA FLUOR 647
-
DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
French translationanticorps
-
Gene target
-
Gene symbolITPKB, ITPKA, ITPKC, CFAP61
-
Short nameAnti-IP3 Receptor
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 647
-
Alternative nameIP3 Receptor Polyclonal Antibody, ALEXA FLUOR 647
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameinositol-trisphosphate 3-kinase B
-
Synonyms gene name
- inositol 1,4,5-trisphosphate 3-kinase B
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1992-04-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinositol-trisphosphate 3-kinase A
-
Synonyms gene name
- inositol 1,4,5-trisphosphate 3-kinase A
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1992-04-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinositol-trisphosphate 3-kinase C
-
Synonyms gene name
- inositol 1,4,5-trisphosphate 3-kinase C
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-06-28
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namecilia and flagella associated protein 61
-
Synonyms gene
-
Synonyms gene name
- chromosome 20 open reading frame 26
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-06-21
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Cilia and flagella associated
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data