AZD6244,ERK kinase inhibitor
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Catalog numberSIH-495-5MG
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Price:
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Size5 mg
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Research Area sCell Signaling , Cancer , Apoptosis , Cancer Growth Inhibitors , Tyrosine Kinase Inhibitors
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CategorySmall Molecules
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Product TypeInhibitor
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CAS No606143-52-6
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MolecularFormulaC17H15BrClFN4O3
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Molecular Weight457.7
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Purity≥98%
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SolubilitySoluble in DMSO (92 mg/ml at 25 °C), water (
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AppearanceWhite to off-white solid
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Storage Temperature-20°C
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Shipping TemperatureShipped Ambient
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DescriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolEPHB2, MAPK1
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Short nameAZD6244 ERK kinase inhibitor
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Alternative nameAZD6244,ERK phosphorylation catalyst suppressor
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Gene info
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Identity
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Gene
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Long gene nameEPH receptor B2
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Synonyms gene
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Synonyms gene name
- EphB2
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-05-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EPH receptors
- MicroRNA protein coding host genes
- Sterile alpha motif domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemitogen-activated protein kinase 1
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-11-05
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Entrez gene record
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Classification
- Mitogen-activated protein kinases
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VEGA ID
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Locus Specific Databases