100ug-Anti- Caspase 8 (CASP8)

• Catalog number
  MAA853Bo21-100ug
• Price
  Please ask
• Size
  100ug

• Organism Species
  Bos taurus; Bovine (Cattle)
• Source
  Monoclonal antibody preparation
• Purification
  Protein A + Protein G affinity chromatography
• Buffer Formulation
  PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
• Item Name
  Caspase 8
• Immunogen
  RPA853Bo01-Recombinant Caspase 8 (CASP8)
• Image number
  1
• Species reactivity
  Bovine
• Sequence of immunogen
  Leu25~Ile175
• Aplication
  WB
• Clonality
  Mouse monoclonal
• Concentration
  1mg/ml
• Alternative Names
  CAP4; FLICE; MACH; MCH5; Cysteinyl Aspartate Specific Proteinases 8; Apoptotic cysteine protease; FADD-homologous ICE/ced-3-like protease; MORT1-associated ced-3 homolog
• Applicable Secondary Antibody
  SAA544Mu08, SAA544Mu09, SAA544Mu07, SAA544Mu19, SAA544Mu18, SAA544Mu17
• Manual link
• Delivery condition
  4℃ with ice bags
• Storage instructions
  Avoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

• Gene target
  100ug   Caspase   CASP8  
• Gene symbol
  CASP8
• Short name
  100ug-Anti- Caspase 8 (CASP8)
• Technique
  anti, antibody to
• Host
  Mouse
• Alternative name
  100ug-antibody to- caspase 8 (caspase 8, apoptosis-related cysteine peptidase)
• Alternative technique
  antibodies
• Alternative to gene target
  caspase 8, apoptosis-related cysteine peptidase, ALPS2B and CAP4 and Casp-8 and FLICE and MACH and MCH5, CASP8 and IDBG-78534 and ENSG00000064012 and 841, cysteine-type endopeptidase activity involved in apoptotic signaling pathway, nuclei, Casp8 and IDBG-157464 and ENSMUSG00000026029 and 12370, CASP8 and IDBG-643207 and ENSBTAG00000015718 and 507481

Gene info

• Identity
  HGNC:1509
• Gene
  CASP8
• Long gene name
  caspase 8
• Synonyms gene name
  • caspase 8, apoptosis-related cysteine protease
  • caspase 8, apoptosis-related cysteine peptidase
• Synonyms
  • MCH5
  • MACH
  • FLICE
  • Casp-8
• GenBank acession
  • U60520
• Locus
  2q33.1
• Discovery year
  1996-11-11
• Entrez gene record
  841
• Pubmed identfication
  • 8681376
  • 8681377
• RefSeq identity
  • NM_001228
• Classification
  • Caspases
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000132821
• Locus Specific Databases
  • CASP8base: Mutation registry for Caspase 8 deficiency
  • LRG_34

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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