Recombinant Mouse Contactin 3 / CNTN3 Protein (His tag)

• Catalog number
  PKSM040389-20µg
• Price
  Please ask
• Size
  20µg

• Synonym
  Pang
• Activity
  NA
• Sequence
  Met1-Gly 1001
• Fusion tag
  C-His
• Accession
  NP_032805.2
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 95 % as determined by SDS-PAGE
• Endotoxin
  < 1.0 EU per μg of the protein as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  110 kDa
• AP Mol Mass
  140-150 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2(TAG-1), Contactin-3(BIG-1), BIG-2, Contactin-5(NB-2) and NB-3. Since their identification in the late 1980s, Contactin-1 and Contactin-2 have been studied extensively. Axonal expression and the neurite extension activity of Contactin-1 and Contactin-2 attracted researchers to study the function of these molecules in axon guidance during development. Contactin-1 and Contactin-2 have come to be known as the principal molecules in the function and maintenance of myelinated neurons. In contrast, the function of the other four members of this subgroup remained unknown until recently. Contactin-3, also known as CNTN3 ( BIG-1 in rat and PANG in mouse ), is a GPI-linked glycoprotein that is expressed on cerebellar Purkinje cells, amygdaloid and thalamic neurons and olfactory granule cells. In the brain, Contactin-3 is expressed in frontal lobe, occipital lobe, cerebellum and amygdala. Contactin-3 contains 4 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. Human Contactin-3 shares 92% aa identity with mouse Contactin-3.The exact function of Contactin-3 is unclear. Contactin-3 may mediate cell-cell interaction and may promote neurite outgrowth.
• Technical data
• Conjugation
  histidine
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Contactin   CNTN3   Protein   His   tag  
• Gene symbol
  CNTN3
• Short name
  Recombinant Mouse Contactin 3 / CNTN3 Protein (His tag)
• Technique
  Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  mouse
• Label
  His
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse Contactin 3 / contactin 3 (plasmacytoma associated) Protein (histidine detection labelled)
• Alternative technique
  rec, murine
• Alternative to gene target
  contactin 3 (plasmacytoma associated), BIG-1 and PANG and PCS, CNTN3 and IDBG-45120 and ENSG00000113805 and 5067, protein binding, Plasma membranes, Cntn3 and IDBG-173374 and ENSMUSG00000030075 and 18488, CNTN3 and IDBG-644917 and ENSBTAG00000007615 and 526697

Gene info

• Identity
  HGNC:2173
• Gene
  CNTN3
• Long gene name
  contactin 3
• Synonyms gene
  • PANG
• Synonyms gene name
  • contactin 3 (plasmacytoma associated)
• Synonyms
  • BIG-1
• GenBank acession
  • AB040929
• Locus
  3p12.3
• Discovery year
  2000-05-26
• Entrez gene record
  5067
• Pubmed identfication
  • 8661054
  • 8586965
• RefSeq identity
  • NM_020872
• Classification
  • I-set domain containing
  • Contactins
• VEGA ID
  OTTHUMG00000158813

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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