Recombinant Rat Contactin 3 / CNTN3 Protein (Fc tag)

• Catalog number
  PKSR030240-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  CNTN3
• Activity
  NA
• Sequence
  Met1-Gly1001
• Fusion tag
  C-Fc
• Accession
  NA
• ExpressedHost
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 85 % as determined by SDS-PAGE
• Endotoxin
  < 1.0 EU per μg of the protein as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  134.8 kDa
• AP Mol Mass
  135 KDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2(TAG-1), Contactin-3(BIG-1), BIG-2, Contactin-5(NB-2) and NB-3. Since their identification in the late 1980s, Contactin-1 and Contactin-2 have been studied extensively. Axonal expression and the neurite extension activity of Contactin-1 and Contactin-2 attracted researchers to study the function of these molecules in axon guidance during development. Contactin-1 and Contactin-2 have come to be known as the principal molecules in the function and maintenance of myelinated neurons. In contrast, the function of the other four members of this subgroup remained unknown until recently. Contactin-3, also known as CNTN3 ( BIG-1 in rat and PANG in mouse ), is a GPI-linked glycoprotein that is expressed on cerebellar Purkinje cells, amygdaloid and thalamic neurons and olfactory granule cells. In the brain, Contactin-3 is expressed in frontal lobe, occipital lobe, cerebellum and amygdala. Contactin-3 contains 4 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. Human Contactin-3 shares 92% aa identity with mouse Contactin-3.The exact function of Contactin-3 is unclear. Contactin-3 may mediate cell-cell interaction and may promote neurite outgrowth.
• Technical data
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Contactin   CNTN3   Protein   tag  
• Gene symbol
  CNTN3
• Short name
  Recombinant Contactin 3 / CNTN3 Protein (Fc tag)
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  Rat
• Label
  Fc Tag
• Species
  Rat, Rats
• Alternative name
  Rec. Rat Contactin 3 / contactin 3 (plasmacytoma associated) Protein (fragment c detection labelled)
• Alternative technique
  rec
• Alternative to gene target
  contactin 3 (plasmacytoma associated), BIG-1 and PANG and PCS, CNTN3 and IDBG-45120 and ENSG00000113805 and 5067, protein binding, Plasma membranes, Cntn3 and IDBG-173374 and ENSMUSG00000030075 and 18488, CNTN3 and IDBG-644917 and ENSBTAG00000007615 and 526697

Gene info

• Identity
  HGNC:2173
• Gene
  CNTN3
• Long gene name
  contactin 3
• Synonyms gene
  • PANG
• Synonyms gene name
  • contactin 3 (plasmacytoma associated)
• Synonyms
  • BIG-1
• GenBank acession
  • AB040929
• Locus
  3p12.3
• Discovery year
  2000-05-26
• Entrez gene record
  5067
• Pubmed identfication
  • 8661054
  • 8586965
• RefSeq identity
  • NM_020872
• Classification
  • I-set domain containing
  • Contactins
• VEGA ID
  OTTHUMG00000158813

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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