anti-TGFB1 Antibody

• Catalog number
  49-553
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  TGF-β-1 is a multifunctional cytokine that belongs to a superfamily of structurally related regulatory proteins, which includes three mammalian TGF-β isoforms (TGF-β-1, -beta-2, and -beta-3), activin/inhibins and bone morphogenetic proteins. The most abundant isoform, TGF-β-1, is a 25 kDa homodimer composed of two 12.5 kDa subunits joined by disulfide bonds. TGF-β-1 is a highly conserved molecule - the amino acid sequence between human and mouse differ only by one residue. Although originally defined by its ability to cause anchorage independent cell growth and changes in cell morphology of rat fibroblasts, subsequent research has revealed that TGF-β is actually a major growth inhibitor for most cell types. It is produced by a wide variety of cell and tissue types during all stages of cell differentiation. TGF-β-1 sources include platelets, bone and soft tissues such as placenta and kidneys.
• Gene names
  TGFB1, CED, DPD1, Diaphyseal dysplasia 1, LAP, Latency-associated peptide, TGF Beta, TGFbeta, TGF-beta 1 protein, TGF-beta-1, TGFB
• Antibodie s label
  unlabelled serum
• Purity
  Immunoaffinity Chromatography
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  TGFB1 antibody was made against Aa 286-293 (of 390) of full-length (including signal peptide) precursor TGFb protein.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  TGFB1 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 ug/mL.
• Suspention pH azide
  0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
• Keep at
  Store TGFB1 antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Human
• Omim nr
  135674
• Ncbi nr
  P01137
• Vial with antibody
  in solution
• NCBI GENE nr
  7040
• GENE symbol
  TGFB1
• Antigene name
  transforming growth factor, beta 1
• Source
  Homo sapiens
• Protein nr
  P01137
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TGFB1  
• Gene symbol
  TGFB1
• Short name
  anti-TGFB1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTGFB1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  transforming growth factor, beta 1, CED and DPD1 and LAP and TGFB and TGFbeta, TGFB1 and IDBG-52846 and ENSG00000105329 and 7040, protein N-terminus binding, nuclei, Tgfb1 and IDBG-158292 and ENSMUSG00000002603 and 21803, TGFB1 and IDBG-638417 and ENSBTAG00000020457 and 282089

Gene info

• Identity
  HGNC:11766
• Gene
  TGFB1
• Long gene name
  transforming growth factor beta 1
• Synonyms gene
  • TGFB
  • DPD1
• Synonyms gene name
  • transforming growth factor, beta 1
• Synonyms
  • CED
  • TGFbeta
• Synonyms name
  • Camurati-Engelmann disease
  • prepro-transforming growth factor beta-1
  • Diaphyseal dysplasia 1, progressive
• GenBank acession
  • X02812
• Locus
  19q13.2
• Discovery year
  2001-06-22
• Entrez gene record
  7040
• Pubmed identfication
  • 10631145
  • 10843814
• Classification
  • Transforming growth factor beta family
• VEGA ID
  OTTHUMG00000182760

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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