Furin/PACE Antibody

• Catalog number
  3873-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  Furin/PACE
• Target Alternative Name
  FES upstream region , FUR , FURIN , PACE , PCSK3 , SPC1
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat, bovine, sheep
• Immunogen Sequence
  Synthetic peptide corresponding to residues surrounding amino acids 779 of mouse Furin/PACE
• Accession
  NP_035176
• Gene Id
  18550
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) affinity purified rabbit anti-Furin/PACE polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~95-110 kDa Furin/PACE. A splice variant (~60 kDa) can also be detected.
• Description
  Furin is a ubiquitous protein located within the trans-Golgi network. It is found in many tissues and cell lines including MDCK, HeLa, HepG2 and NIH-3T3. Furin is a proprotein convertase that is responsible for the proteolytic maturation of many precursor proteins that are secreted from the constitutive secretory pathway
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Furin/PACE  
• Gene symbol
  SCYL3, FURIN
• Short name
  Furin/PACE Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  furin (paired basic amino acid cleaving enzyme)/PACE (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  furin (paired basic amino acid cleaving enzyme), FUR and PACE and PCSK3 and SPC1, FURIN and IDBG-30430 and ENSG00000140564 and 5045, nerve growth factor binding, Cell surfaces, Furin and IDBG-195335 and ENSMUSG00000030530 and 18550, FURIN and IDBG-629479 and ENSBTAG00000002939 and 281374

Gene info

• Identity
  HGNC:19285
• Gene
  SCYL3
• Long gene name
  SCY1 like pseudokinase 3
• Synonyms gene name
  • SCY1-like 3 (S. cerevisiae)
  • SCY1-like, kinase-like 3
• Synonyms
  • PACE-1
  • PACE1
• Synonyms name
  • ezrin-binding partner PACE-1
• GenBank acession
  • BC014662
• Locus
  1q24.2
• Discovery year
  2005-03-01
• Entrez gene record
  57147
• Pubmed identfication
  • 12651155
• RefSeq identity
  • NM_181093
• Classification
  • SCY1 like pseudokinases
• VEGA ID
  OTTHUMG00000035941

Gene info

• Identity
  HGNC:8568
• Gene
  FURIN
• Long gene name
  furin, paired basic amino acid cleaving enzyme
• Synonyms gene
  • PCSK3
  • FUR
  • PACE
• Synonyms gene name
  • paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein)
  • furin (paired basic amino acid cleaving enzyme)
• Synonyms
  • SPC1
• Synonyms name
  • proprotein convertase subtilisin/kexin 3
  • subtilisin-like proprotein convertase 1
• GenBank acession
  • X17094
• Locus
  15q26.1
• Discovery year
  1991-08-08
• Entrez gene record
  5045
• Pubmed identfication
  • 2251280
  • 1741956
• RefSeq identity
  • NM_002569
• Classification
  • Proprotein convertase subtilisin/kexin family
• VEGA ID
  OTTHUMG00000149831

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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