Tim-3 Antibody

• Catalog number
  3808-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  Tim
• Target Alternative Name
  tim-3, tim3, tim 3, TIMD3, TIMD-3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell membrane protein 3
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Synthetic peptide surrounding amino acid residue 285 of human Tim-3
• Accession
  Q8TDQ0
• Gene Id
  84868
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot and Immunohistochemistry (5 µg/ml)
• Application And Usages
  Western blotting (0.5-4 µg/ml) and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. The antibody detects a 33 kDa human Tim-3 on SDS-PAGE immunoblots. Other applications have not been determined.
• Description
  As a member of the T cell immunoglobulin and mucin domain (TIM) family, Tim-3 is reported to promote or terminate Th1 immunity and is thought to influence a range of inflammatory conditions. It is constitutively expressed in a subset of murine IFNgamma-secreting Th1 cells, but not Th2 cells, in both human and mice. Additionally, Tim-3 is expressed dendritic cells, and by a subset of CD4+ cells where its levels of expression increase upon anti-CD3/28 stimulation. This molecule is also highly expressed in in vitro polarized Th1 cells, and at lower levels in Th17 cells. It is known to synergize with Toll-like receptors and is thought to regulate Th1 and Th17 cytokine secretion.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Tim-3  
• Gene symbol
  HAVCR2
• Short name
  Tim-3 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Tim-3 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18437
• Gene
  HAVCR2
• Long gene name
  hepatitis A virus cellular receptor 2
• Synonyms
  • Tim-3
  • TIM3
  • FLJ14428
  • TIMD3
  • CD366
• Synonyms name
  • T-cell immunoglobulin mucin family member 3
• GenBank acession
  • AK027334
• Locus
  5q33.3
• Discovery year
  2002-12-04
• Entrez gene record
  84868
• Pubmed identfication
  • 11823861
• RefSeq identity
  • NM_032782
• Classification
  • V-set domain containing
• VEGA ID
  OTTHUMG00000130249

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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