anti- NEDD4 antibody

• Catalog number
  FNab05645
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
• Immunogen
  neural precursor cell expressed, developmentally down-regulated 4
• Synonyms
  KIAA0093, NEDD4-1
• Calculated MW
  120 kDa
• Uniprot ID
  P46934
• Specificity
  Human
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab05645( NEDD4 Antibody) at dilution of 1:50
• Image4
  C6 cells were subjected to SDS PAGE followed by western blot with FNab05645(NEDD4 antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NEDD4  
• Gene symbol
  NEDD4, NEDD4L
• Short name
  anti- NEDD4 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- NEDD4 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7727
• Gene
  NEDD4
• Long gene name
  NEDD4 E3 ubiquitin protein ligase
• Synonyms gene name
  • neural precursor cell expressed, developmentally down-regulated 4
  • neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
• Synonyms
  • KIAA0093
  • MGC176705
  • NEDD4-1
  • RPF1
• Synonyms name
  • receptor-potentiating factor 1
• GenBank acession
  • D42055
• Locus
  15q21.3
• Discovery year
  1994-01-21
• Entrez gene record
  4734
• Pubmed identfication
  • 9073511
  • 8649367
• RefSeq identity
  • NM_198400
• Classification
  • HECT domain containing
• VEGA ID
  OTTHUMG00000132015

Gene info

• Identity
  HGNC:7728
• Gene
  NEDD4L
• Long gene name
  NEDD4 like E3 ubiquitin protein ligase
• Synonyms gene name
  • neural precursor cell expressed, developmentally down-regulated 4-like
  • neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
• Synonyms
  • KIAA0439
  • RSP5
  • NEDD4-2
• GenBank acession
  • AF210730
• Locus
  18q21.31
• Discovery year
  2000-03-14
• Entrez gene record
  23327
• Pubmed identfication
  • 10594025
  • 11244092
  • 18322022
• Classification
  • HECT domain containing
  • C2 domain containing
• VEGA ID
  OTTHUMG00000179875

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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