DS5a, Drosophila 26S proteasome subunit Rpn10

• Catalog number
  AS01 012
• Price
  Please ask
• Size
  50 µl

• Available ordering format
  Lyophilized
• Immunogen
  Drosophila mealnogaster 26S Proteasome subunit S5a also known as Rpn10, p54. Antigen sequence is also conserved in Arabidopsis thaliana AT4G38630
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Clone
  Polyclonal
• Purification
  Serum
• How to reconstitute
  For reconstitution add 50 µl of sterile water.
• Storage condition
  store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
• Verified applications
  western blot (WB)
• Connected products
  ASA01 019 | human 26S proteasome subunitSecondary antibodies
• Recommended dilutions for use
  1:2000 (WB)
• Molecular weight expected аpparent
  42.6 | 54 kDa (Drosophila), 40 kDa (A. thaliana)
• Verified reactivity
  Arabidopsis thaliana, Drosophila melanogaster
• Possible reactivity
  bovine, mouse, pig, salmon, rat,
• No reactivity
  no confirmed exceptions from predicted reactivity known in the moment
• Supplementary information
  Contact Gentaur support center at [email protected]
• References
  Nguyen at al (2012). An upstream regulator of the 26S proteasome modulates organ size in Arabidopsis thaliana. Plant J. Dec 17.Lundgren et al. (2003). Use of RNA interference and complementation to study the function of the Drosophila and human 26S proteasome subunit S13. Mol Cel Biol 23:5320-5330.
• Scientific context
  Proteasome-dependent degradation serves an essential role in the removal of a wide variety of key nuclear and cytosolic proteins. Substrates are targeted for proteolysis by the ubiquitin pathway before being degraded by the 26 S proteasome. The subunit of the proteasome, S5a, was identified to bind to polyubiquitin in vitro and thus proposed to act as a substrate recognition component.
• Notes
  None
• Protein number
  Refer to NCBI
• TAIR number
  AT4G38630
• Hyperlink

• Gene target
  DS5a   26S   proteasome   subunit   Rpn10  
• Short name
  DS5a, 26S proteasome subunit Rpn10
• Species
  Drosophila, Drosophila subspecies d. Megalonaster or the fruit fly is used in genetic research because of the short life cycle and the possibility of knock-out and knock-ins with Cas9 for ends-in gene targets like CRISPR.Cas9 and TALEN vectors . Drosophilas
• Alternative name
  DS5a, Drosophila 26S protein degradation aggregate functionnal sequence Rpn10

Similar products