Filters
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing

AMPK alpha 2 Antibody

AMPK alpha 2 Antibody is available 0 time from Bioss primary unconjugated antibodies labs

Synonym names AMPK; AMPK2; PRKAA; AMPKa2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; PRKAA2
Clonality Polyclonal antibody
Category Primary Antibodies
Also known as AMPK alpha 2 PAb
Modification(s) None
Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AMPK alpha 2
Cross reactivity Human, Mouse, Rat
Swiss Prot P54646
Specificity This is a highly specific antibody against AMPK alpha 2.
Immunogen range 375-425/552
Long name AMPK alpha 2 Primary Polyclonal Antibody
Subcellular location Cytoplasm, Nucleus
Gene ID number 5563
Tested Applications WB, IHC-P, IF(IHC-P)
Recommended dilutions WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Modification site(s) Unmodified antibody
Background of the target antigen Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Regulates lipid synthesis by phosphorylating and inactivating lipid metabolic enzymes such as ACACA, ACACB, GYS1, HMGCR and LIPE; regulates fatty acid and cholesterol synthesis by phosphorylating acetyl-CoA carboxylase (ACACA and ACACB) and hormone-sensitive lipase (LIPE) enzymes, respectively. Regulates insulin-signaling and glycolysis by phosphorylating IRS1, PFKFB2 and PFKFB3. AMPK stimulates glucose uptake in muscle by increasing the translocation of the glucose transporter SLC2A4/GLUT4 to the plasma membrane, possibly by mediating phosphorylation of TBC1D4/AS160. Regulates transcription and chromatin structure by phosphorylating transcription regulators involved in energy metabolism such as CRTC2/TORC2, FOXO3, histone H2B, HDAC5, MEF2C, MLXIPL/ChREBP, EP300, HNF4A, p53/TP53, SREBF1, SREBF2 and PPARGC1A. Acts as a key regulator of glucose homeostasis in liver by phosphorylating CRTC2/TORC2, leading to CRTC2/TORC2 sequestration in the cytoplasm. In response to stress, phosphorylates 'Ser-36' of histone H2B (H2BS36ph), leading to promote transcription. Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2, RPTOR and ATG1/ULK1: in response to nutrient limitation, negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex and by phosphorylating and activating TSC2.
Concentration 1ug per 1ul
Purification method This antibody was purified via Protein A.
Cross reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Target Antigen AMPK alpha 2
Storage conditions Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Conjugation Unconjugated
Clone number Polyclonal antibody
Description The AMPK alpha 2 Antibody is a α- or alpha protein sometimes glycoprotein present in blood.
Properties If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetAMPK alpha
Short name AMPK alpha 2 Antibody
Technique Antibody
Alternative name AMPK a 2 (Antibody to)
Alternative technique antibodies
Similar products
AMPKalpha1 2 Polyclonal Antibody Suppplier: MyBioSource
Price: 195.15 USD
Anti AMPK alpha Polyclonal antibody Suppplier: QED Biosciences
Price: 533.83 USD
AMPK alpha 1 Antibody Suppplier: Bioss Primary Unconjugated Antibodies
Price: 298.40 USD
AMPK alpha 1 Ser496 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 397.28 USD
AMPK alpha 1 2 antibody Suppplier: fitzgerald
Price: 609.28 USD
AMPK alpha 2 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 377.54 USD
AMPK alpha 2 Antibody Suppplier: NJS poly
Price: 225.79 USD
AMPK alpha 1 antibody Suppplier: MyBioSource
Price: 0.00 USD
AMPK alpha 1 Antibody Suppplier: MBS Monoclonals
Price: 445.90 USD
AMPKalpha Antibody Suppplier: MyBioSource
Price: 0.00 USD
AMPK alpha 1 Antibody - C-terminal region Suppplier: aviva
Price: 481.07 USD
AMPKalpha2 Polyclonal Antibody Suppplier: MyBioSource
Price: 419.80 USD
AMPK alpha 2 Ser176 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 397.28 USD
AMPK alpha pT172 Antibody Suppplier: abbex
Price: 63.54 USD
AMPK alpha PRKAA1 Antibody S487 Suppplier: MyBioSource
Price: 250.75 USD
AMPK alpha 2 antibody Suppplier: genways
Price: 603.61 USD
AMPK alpha1 Monoclonal Antibody Suppplier: MyBioSource
Price: 376.69 USD
Ask
Ajax processing
Close
AMPK alpha 2 Antibody - Bioss Primary Unconjugated Antibodies
Filters
+32-(0)1-658-90-45 lieven@gentaur.com
Contact us
Ajax processing
Close
Chat with gentaur.com employee