PIAS1, CT E3 SUMO-protein Ligase PIAS1, Protein Inhibitor of Activated STAT Protein 1, Gu Binding Protein, GBP, RNA Helicase II Binding Protein, DEAD/H Box-binding Protein 1, DDXBP1)

• Catalog number
  MBS625913
• Price
  Please ask
• Size
  0,2 mL

• Other size
  please contact us to order other different size
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell.

• Gene target
  PIAS1   SUMO-protein   Ligase   PIAS1   Protein   Inhibitor   Activated   STAT   Protein   Binding   Protein   GBP   RNA   Helicase   Binding   Protein   DEAD/H   Box-binding   Protein   DDXBP1  
• Gene symbol
  PIAS1, SUMO1, LGALS1, TMEM132A, STAT6, SOAT1, HADHA
• Short name
  PIAS1, CT E3 SUMO-protein Ligase PIAS1, Protein Inhibitor of Activated STAT Protein 1, Gu Binding Protein, GBP, RNA Helicase II Binding Protein, DEAD/H Box-binding Protein 1, DDXBP1)
• Technique
  RNAs are to store at -70 C
• Alternative name
  PIAS1, CT E3 SUMO-protein Ligase PIAS1, Protein suppressor on Activated Signal transducer and activation on transcription Protein 1, Gu Binding Protein, GBP, RNA Helicase II Binding Protein, DEAD/H Box-binding Protein 1, DDXBP1)

Gene info

• Identity
  HGNC:2752
• Gene
  PIAS1
• Long gene name
  protein inhibitor of activated STAT 1
• Synonyms gene
  • DDXBP1
• Synonyms gene name
  • DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1
• Synonyms
  • GBP
  • GU/RH-II
  • ZMIZ3
• Synonyms name
  • zinc finger, MIZ-type containing 3
• GenBank acession
  • AF077951
• Locus
  15q23
• Discovery year
  1998-11-06
• Entrez gene record
  8554
• Pubmed identfication
  • 9724754
  • 9177271
  • 19526197
• Classification
  • Zinc fingers MIZ-type
• VEGA ID
  OTTHUMG00000172645

Gene info

• Identity
  HGNC:12502
• Gene
  SUMO1
• Long gene name
  small ubiquitin like modifier 1
• Synonyms gene
  • UBL1
• Synonyms gene name
  • ubiquitin-like 1 (sentrin)
  • SMT3 suppressor of mif two 3 homolog 1 (yeast)
  • SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
• Synonyms
  • PIC1
  • GMP1
  • SMT3C
  • SUMO-1
  • SMT3H3
  • OFC10
• GenBank acession
  • U38784
• Locus
  2q33.1
• Discovery year
  1996-06-04
• Entrez gene record
  7341
• Pubmed identfication
  • 8812453
  • 8906799
• RefSeq identity
  • NM_003352
• VEGA ID
  OTTHUMG00000132839

Gene info

• Identity
  HGNC:6561
• Gene
  LGALS1
• Long gene name
  galectin 1
• Synonyms gene name
  • lectin, galactoside-binding, soluble, 1
• Synonyms
  • GBP
• Locus
  22q13.1
• Discovery year
  1991-09-13
• Entrez gene record
  3956
• Pubmed identfication
  • 1988031
  • 12271131
• RefSeq identity
  • NM_002305
• Classification
  • Receptor ligands
  • Galectins
• VEGA ID
  OTTHUMG00000150661

Gene info

• Identity
  HGNC:31092
• Gene
  TMEM132A
• Long gene name
  transmembrane protein 132A
• Synonyms gene
  • HSPA5BP1
• Synonyms gene name
  • heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) binding protein 1
• Synonyms
  • GBP
  • FLJ20539
• GenBank acession
  • AK000546
• Locus
  11q12.2
• Discovery year
  2004-02-04
• Entrez gene record
  54972
• Pubmed identfication
  • 12514190
  • 29088312
• RefSeq identity
  • NM_017870
• VEGA ID
  OTTHUMG00000167803

Gene info

• Identity
  HGNC:11368
• Gene
  STAT6
• Long gene name
  signal transducer and activator of transcription 6
• Synonyms gene name
  • signal transducer and activator of transcription 6, interleukin-4 induced
• Synonyms
  • D12S1644
  • IL-4-STAT
• GenBank acession
  • BC005823
  • BQ028928
• Locus
  12q13.3
• Discovery year
  1995-11-09
• Entrez gene record
  6778
• Pubmed identfication
  • 9605853
  • 8085155
• RefSeq identity
  • NM_003153
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000171194
• Locus Specific Databases
  • LRG_1369

Gene info

• Identity
  HGNC:11177
• Gene
  SOAT1
• Long gene name
  sterol O-acyltransferase 1
• Synonyms gene
  • SOAT
  • STAT
• Synonyms gene name
  • sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
• Synonyms
  • ACAT
  • ACAT1
• Synonyms name
  • acyl-Coenzyme A: cholesterol acyltransferase
• GenBank acession
  • L21934
• Locus
  1q25.2
• Discovery year
  1998-11-04
• Entrez gene record
  6646
• Pubmed identfication
  • 8407899
• RefSeq identity
  • NM_003101
• VEGA ID
  OTTHUMG00000035253

Gene info

• Identity
  HGNC:4801
• Gene
  HADHA
• Long gene name
  hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
• Synonyms gene name
  • hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
  • hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
• Synonyms
  • GBP
  • LCEH
  • LCHAD
  • MTPA
• Synonyms name
  • gastrin-binding protein
  • long-chain-3-hydroxyacyl-CoA dehydrogenase
  • long-chain 2-enoyl-CoA hydratase
  • mitochondrial trifunctional protein, alpha subunit
• GenBank acession
  • D16480
• Locus
  2p23.3
• Discovery year
  1994-12-16
• Entrez gene record
  3030
• Pubmed identfication
  • 9605857
  • 7918661
• RefSeq identity
  • NM_000182
• VEGA ID
  OTTHUMG00000096979
• Locus Specific Databases
  • LRG_747

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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