Anti-Down Regulator Of Transcription 1, TBP Binding (DR1)-Rabbit polyclonal Antibody
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Catalog numberPAB259Hu01
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PricePlease ask
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Size10ug
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Organism SpeciesHomo sapiens (Human)
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SourcePolyclonal antibody preparation
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PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
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Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
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Item NameDown Regulator Of Transcription 1, TBP Binding
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ImmunogenRPB259Hu01-Recombinant Down Regulator Of Transcription 1, TBP Binding (DR1)
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Image number2
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Species reactivityHuman
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Sequence of immunogenDR1 (Ala2~Glu170)
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AplicationWB,IHC
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ClonalityRabbit polyclonal
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Concentration500ug/ml
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Alternative NamesNC2; NC2-BETA; Negative Cofactor 2; TATA-binding protein-associated phosphoprotein
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Applicable Secondary AntibodySAA544Rb59, SAA544Rb58, SAA544Rb57, SAA544Rb18, SAA544Rb19
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Delivery condition4℃ with ice bags
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Storage instructionsAvoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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PropertiesIf you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by Cloud Clone Corp. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cloud Clone Corp adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolTBP, DR1, CHRFAM7A, PSMC3, PSMC4
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Short nameAnti-Down Regulator Of Transcription 1, TBP Binding (DR1)-Rabbit polyclonal Antibody
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TechniquePolyclonal, Antibody, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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HostRabbit, Rabbits
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Alternative nameAntibody toDown Regulator on Transcription 1, TBP Binding (DR1)-production species: rabbit polyclonal (antibody to-)
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Alternative techniquepolyclonals, antibodies, rabbit-anti
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Gene info
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Identity
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Gene
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Long gene nameTATA-box binding protein
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-05-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- General transcription factor IID complex subunits
- General transcription factor IIIB complex subunits
- General transcription factors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedown-regulator of transcription 1
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Synonyms gene name
- down-regulator of transcription 1, TBP-binding (negative cofactor 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-07-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ATAC complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion
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Synonyms gene name
- CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameproteasome 26S subunit, ATPase 3
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Synonyms gene name
- proteasome (prosome, macropain) 26S subunit, ATPase, 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-12-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Proteasome
- AAA ATPases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameproteasome 26S subunit, ATPase 4
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Synonyms gene
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Synonyms gene name
- proteasome (prosome, macropain) 26S subunit, ATPase, 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-12-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- AAA ATPases
- Proteasome
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.
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Tree numbers
- E05.393.335.500
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Qualifiersethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data
