HRP-Linked Polyclonal Antibody to Down Regulator Of Transcription 1, TBP Binding (DR1)

• Catalog number
  MBS2053276
• Price
  Please ask
• Size
  0,1 mg

• Other size
  please contact us to order other different size
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Conjugation
  HRP Conjugated
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• Description
  The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
• French translation
  anticorps

• Gene target
  Linked   Down   Regulator   Transcription   TBP   Binding   DR1  
• Gene symbol
  TBP, DR1, CHRFAM7A, PSMC3, PSMC4
• Short name
  -Linked Polyclonal Antibody Down Regulator Of Transcription 1, TBP Binding (DR1)
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  HRP
• Alternative name
  horseradish peroxidase-Linked polyclonal (antibody to-) to Down Regulator on Transcription 1, TBP Binding (DR1)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:11588
• Gene
  TBP
• Long gene name
  TATA-box binding protein
• Synonyms gene
  • GTF2D1
  • SCA17
• Synonyms
  • TFIID
• GenBank acession
  • M55654
• Locus
  6q27
• Discovery year
  1993-05-26
• Entrez gene record
  6908
• Pubmed identfication
  • 2194289
  • 11448935
• RefSeq identity
  • NM_003194
• Classification
  • General transcription factor IID complex subunits
  • General transcription factor IIIB complex subunits
  • General transcription factors
• VEGA ID
  OTTHUMG00000016084

Gene info

• Identity
  HGNC:3017
• Gene
  DR1
• Long gene name
  down-regulator of transcription 1
• Synonyms gene name
  • down-regulator of transcription 1, TBP-binding (negative cofactor 2)
• Synonyms
  • NC2-BETA
  • NC2B
  • NCB2
• Synonyms name
  • negative cofactor 2
  • negative cofactor 2 beta
• GenBank acession
  • M97388
• Locus
  1p22.1
• Discovery year
  1996-07-11
• Entrez gene record
  1810
• Pubmed identfication
  • 1339312
  • 9040789
• RefSeq identity
  • NM_001938
• Classification
  • ATAC complex
• VEGA ID
  OTTHUMG00000010862

Gene info

• Identity
  HGNC:15781
• Gene
  CHRFAM7A
• Long gene name
  CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion
• Synonyms gene name
  • CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
• Synonyms
  • D-10
  • CHRNA7-DR1
• GenBank acession
  • AF029838
• Locus
  15q13.2
• Discovery year
  2001-06-29
• Entrez gene record
  89832
• Pubmed identfication
  • 11829490
• RefSeq identity
  • NM_148911
• VEGA ID
  OTTHUMG00000175645

Gene info

• Identity
  HGNC:9549
• Gene
  PSMC3
• Long gene name
  proteasome 26S subunit, ATPase 3
• Synonyms gene name
  • proteasome (prosome, macropain) 26S subunit, ATPase, 3
• Synonyms
  • TBP1
  • TBP-1
  • RPT5
• GenBank acession
  • M34079
• Locus
  11p11.2
• Discovery year
  1995-12-06
• Entrez gene record
  5702
• Pubmed identfication
  • 9048938
  • 9473509
• RefSeq identity
  • NM_002804
• Classification
  • Proteasome
  • AAA ATPases
• VEGA ID
  OTTHUMG00000167692

Gene info

• Identity
  HGNC:9551
• Gene
  PSMC4
• Long gene name
  proteasome 26S subunit, ATPase 4
• Synonyms gene
  • MIP224
• Synonyms gene name
  • proteasome (prosome, macropain) 26S subunit, ATPase, 4
• Synonyms
  • TBP7
  • S6
  • MGC8570
  • MGC13687
  • MGC23214
  • TBP-7
  • RPT3
• Synonyms name
  • protease 26S subunit 6
  • Tat-binding protein 7
  • MB67 interacting protein
• GenBank acession
  • U27515
• Locus
  19q13.11-q13.13
• Discovery year
  1995-12-06
• Entrez gene record
  5704
• Pubmed identfication
  • 9473509
  • 8603043
• RefSeq identity
  • NM_006503
• Classification
  • AAA ATPases
  • Proteasome
• VEGA ID
  OTTHUMG00000182577

MeSH Data

• Name
  Gene Knockdown Techniques
• Concept
  Scope note: The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.
• Tree numbers
  • E05.393.335.500
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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