TRAIL, aa261-277 (TNF-Related Apoptosis Inducing Ligand, Apo2L, TL2, TNFSF10)
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Catalog numberMBS6000613
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PricePlease ask
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Size0,1 mg
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Other sizeplease contact us to order other different size
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DescriptionThis 1 is suited for programmed cell-death studies. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
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GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbolTNFSF10, TNF, TNFRSF1A, TNFRSF1B, LTBR, MT-TL2, TNFRSF10B
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Short nameTRAIL, aa261-277 (TNF- Apoptosis Ligand, Apo2L, TL2, TNFSF10)
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Techniqueapoptosis, apoptosis pathway
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Alternative nameTRAIL, aa261-277 (tumor necrosis factor-Related programmed cellular destruction Inducing Ligand, Apo2L, TL2, tumor necrosis factor (ligand) superfamily, member 10)
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Alternative techniquecelldeath
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Alternative to gene targettumor necrosis factor (ligand) superfamily, member 10, Apo-2L and APO2L and CD253 and TL2 and TRAIL, TNFSF10 and IDBG-65161 and ENSG00000121858 and 8743, metal ion binding, Extracellular, Tnfsf10 and IDBG-134362 and ENSMUSG00000039304 and 22035, BT.20790 and IDBG-636176 and ENSBTAG00000018994 and 507215
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Gene info
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Identity
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Gene
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Long gene nameTNF superfamily member 10
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 10
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Pubmed identfication
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Classification
- CD molecules
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1A
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1B
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelymphotoxin beta receptor
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-03-12
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemitochondrially encoded tRNA-Leu (CUN) 2
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Synonyms gene
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Synonyms gene name
- tRNA leucine 2 (CUN)
- mitochondrially encoded tRNA leucine 2 (CUN)
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Synonyms
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Locus
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Discovery year1989-10-12
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Entrez gene record
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Pubmed identfication
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Classification
- Mitochondrially encoded transfer RNAs
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 10b
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 10b
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID