CD328 / Siglec-7 monoclonal antibody

• Catalog number
  11-799-C100
• Price
  Please ask
• Size
  100ug

• Long name
  Mouse Monoclonal Antibody against Human CD328 / Siglec-7, Clone: 6-434
• Antigen
  CD328 / Siglec-7
• Species reactivity
  Human (Homo sapiens)
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  6-434
• Applications
  FC
• Immunogen
  human dendritic cells
• Format conjugation
  purified; unconjugated
• Specificity
  The mouse monoclonal antibody 6-434 recognizes CD328 (Siglec-7), a 75 kDa transmembrane glycoprotein expressed mainly on NK cells, dendritic cells and monocytes. _x000D_ _x000D_ HLDA 8; WS Code ARN-80652_x000D_
• Research area
  CD and Related Antigens (Human)
• Concentration
  1 mg/ml
• Storage buffer
  Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
• Shipping and storage
  Mouse Monoclonal Antibody against Human CD328 / Siglec-7, Clone: 6-434 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  CD328, also known as Siglec-7 or p75/AIRM1, is a 75 kDa type I transmembrane glycoprotein of sialic acid-binding immunoglobulin-like lectin (Siglec) family. CD328 binds to sialylated glycans with alpha2,6 sialyl and alpha2,8 disyalyl residues and mediates sialic acid-dependent cell-cell binding. As it contains in its intracellular part the immunoreceptor tyrosine-based inhibitory motif (ITIM), it serves as an inhibitory receptor, e.g. of NK cells.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by protein-A affinity chromatography
• Datasheet
• References
  Contact us for the most recent list of references
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  CD328   Siglec-7   monoclonal  
• Gene symbol
  SIGLEC7
• Short name
  Anti-CD328 / Siglec-7 Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgG1
• Alternative name
  Mouse Monoclonal to CD328 / Siglec-7
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10876
• Gene
  SIGLEC7
• Long gene name
  sialic acid binding Ig like lectin 7
• Synonyms gene
  • SIGLEC19P
  • SIGLECP2
• Synonyms gene name
  • sialic acid binding Ig-like lectin 19, pseudogene
  • sialic acid binding Ig-like lectin, pseudogene 2
  • sialic acid binding Ig-like lectin 7
• Synonyms
  • SIGLEC-7
  • p75/AIRM1
  • QA79
  • CD328
• GenBank acession
  • AF170485
• Locus
  19q13.41
• Discovery year
  2000-01-26
• Entrez gene record
  27036
• Pubmed identfication
  • 10567377
• RefSeq identity
  • NM_016543
• Classification
  • CD molecules
  • Sialic acid binding Ig like lectins
  • V-set domain containing
• VEGA ID
  OTTHUMG00000182895

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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