Siglec 7 (Sialic Acid Binding Immunoglobulin-like Lectin 7, Sialic Acid-binding Ig-like Lectin 7, Siglec-7, Adhesion Inhibitory Receptor Molecule 1, AIRM1, AIRM-1, CD328 Antigen, CDw328, D-siglec, P75, QA79) (FITC)
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Catalog numberMBS604764
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PricePlease ask
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Size5x0.1 mg
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Products_typeAntibody
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Products_short_name[Siglec 7]
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Products_name_syn[Anti -Siglec 7 (Sialic Acid Binding Immunoglobulin-like Lectin 7, Sialic Acid-binding Ig-like Lectin 7, Siglec-7, Adhesion Inhibitory Receptor Molecule 1, AIRM1, AIRM-1, CD328 Antigen, CDw328, D-siglec, P75, QA79) (FITC)]
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Other_names[sialic acid-binding Ig-like lectin 7 isoform 2; Sialic acid-binding Ig-like lectin 7; sialic acid-binding Ig-like lectin 7; AIRM-1; QA79 membrane protein; sialic acid binding immunoglobulin-like lectin 7; adhesion inhibitory receptor molecule 1, siglec-7; sialic acid binding Ig-like lectin 7; Adhesion inhibitory receptor molecule 1; AIRM-1; CDw328; D-siglec; QA79 membrane protein; p75]
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Other_gene_names[SIGLEC7; SIGLEC7; p75; QA79; AIRM1; CD328; CDw328; D-siglec; SIGLEC-7; SIGLECP2; SIGLEC19P; p75/AIRM1; AIRM1; Siglec-7; AIRM-1]
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ClonalityMonoclonal
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Clone[10B2201]
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ReactivityHuman
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SpecificityRecognizes human CDw328.
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PurityAffinity Purified Purified by Protein G affinity chromatography.
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FormSupplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
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Storage_stabilityMay be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
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Tested_applicationFlow Cytometry (FC/FACS)
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Descriptioncell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the Siglec 7 (Sialic Acid Binding Immunoglobulin-like Lectin 7, Sialic Acid-binding Ig-like Lectin 7, Siglec-7, Adhesion Inhibitory Receptor Molecule 1, AIRM1, AIRM-1, CD328 Antigen, CDw328, D-siglec, P75, QA79) (FITC). Antigens are peptides or recombinant or native dependent on the production method. Whole adhesion and interacting molecules are present in lysates used as reference for ELISA quantification of these molecules and their subunits. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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PropertiesThis MyBioSource Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MyBioSource FITC is highly sensitive to pH extremes.
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ConjugationAnti-FITC Antibody
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Gene target
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Gene symbolSIGLEC7, PSIP1, TCF3, TNFRSF1B, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1
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Short nameSiglec 7 (Sialic Acid Binding Immunoglobulin-like Lectin 7, Sialic Acid-binding Ig-like Lectin 7, Siglec-7, Adhesion Inhibitory Receptor Molecule 1, AIRM1, AIRM-1, CD328 Antigen, CDw328, D-siglec, P75, QA79) (FITC)
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Techniqueantigen, FITC, antigenes, Fluorescein
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HostMouse
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IsotypeIgG1
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LabelFITC
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Alternative nameSiglec 7 (Sialic Acid Binding Immunoglobulin-like Lectin 7, Sialic Acid-binding Ig-like Lectin 7, Siglec-7, Adhesion Inhibitory Receptor Molecule 1, AIRM1, AIRM-1, CD328 protein, CDw328, D-siglec, P75, QA79) (fluorecein)
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Alternative techniqueantigenes, fluorescine
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Gene info
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Identity
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Gene
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Long gene namesialic acid binding Ig like lectin 7
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Synonyms gene
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Synonyms gene name
- sialic acid binding Ig-like lectin 19, pseudogene
- sialic acid binding Ig-like lectin, pseudogene 2
- sialic acid binding Ig-like lectin 7
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-01-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Sialic acid binding Ig like lectins
- V-set domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePC4 and SFRS1 interacting protein 1
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Synonyms gene
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Synonyms gene name
- PC4 and SFRS1 interacting protein 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-09-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Heparin binding growth factor family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametranscription factor 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1990-07-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Basic helix-loop-helix proteins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1B
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
MeSH Data
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Name
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ConceptScope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
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Tree numbers
- E01.370.225.500.607.512.240
- E01.370.225.750.551.512.240
- E05.200.500.607.512.240
- E05.200.750.551.512.240
- E05.478.583.375
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data