EHop-016

• Catalog number
  9595-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  4-N-(9-ethylcarbazol-3-yl)-2-N-(3-morpholin-4-ylpropyl)pyrimidine-2,4-diamine
• Description
  EHop-016 is an analog of NSC-23766 (Cat. No. 1941) that acts as a potent inhibitor of Rac GTPase (IC₅₀ = 1.1 µM for Rac1).  The IC₅₀ of 1.1 μM for Rac inhibition by EHop-016 is ∼100-fold lower than for NSC-23766. EHop-016 is specific for Rac1 and Rac3 at concentrations of ≤5 μM. At higher concentrations, EHop-016 inhibits the close homolog Cdc42.
• CAS Number
  1380432-32-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₅H₃₀N₆O
• Molecular Weight
  430.55
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent inhibitor of Rac GTPase
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  51031035
• PubChem CID Link
• SMILES
  CCN1C2=C(C=C(C=C2)NC3=NC(=NC=C3)NCCCN4CCOCC4)C5=CC=CC=C51
• InChi
  InChI=1S/C25H30N6O/c1-2-31-22-7-4-3-6-20(22)21-18-19(8-9-23(21)31)28-24-10-12-27-25(29-24)26-11-5-13-30-14-16-32-17-15-30/h3-4,6-10,12,18H,2,5,11,13-17H2,1H3,(H2,26,27,28,29)
• InChi Key
  AFTZZRFCMOAFCR-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  EHop-016  
• Short name
  EHop-016
• Alternative name
  EHop-016

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