Tumor Necrosis Factor-Receptor 1 (TNF-R1) Polyclonal Antibody
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Catalog numberMBS194491
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Price:
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Size0.2 mg
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Products_typeAntibody
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Products_short_name[TNF-R1]
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Products_gene_name[TNF-R1]
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ClonalityPolyclonal
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SpecificityTNF-R1 Antibody This antibody detects a 55 kDa protein on HeLa heat shocked cell lysate SDSPAGE immunoblots, corresponding to the molecular weight of TNF-R1. This antibody reacts with human, mouse, rat, hamster, bovine, rabbit, monkey, sheep, canine, pig, Drosophila, Xenopus, and yeast TNF-R1.
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PurityAffinity Purified
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Storage_stabilityStore frozen product at or below -20 degree C. Thawed product may be stored for 2-4 weeks at 4 degree C. For optimal storage, aliquot and store at -20 degree C.
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Tested_applicationImmunohistochemistry; Western Blot
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PropertiesIf you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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French translationanticorps
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Gene target
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Gene symbolTNFRSF1A, TNF, C17orf75, CDCA7L, TNFRSF1B, CNEP1R1, LTBR, CXCL11, PNPLA7, PCAT6
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Short nameTumor Necrosis Factor-Receptor 1 (TNF-R1) Polyclonal Antibody
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TechniquePolyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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HostRabbit
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Alternative nameTumor Necrosis Factor-Receptor 1 (tumor necrosis factor-R1) polyclonal (antibody to-)
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Alternative techniquepolyclonals, antibodies
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Alternative to gene targettumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
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Tissuetumor
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Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1A
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nametumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namechromosome 17 open reading frame 75
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-01-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecell division cycle associated 7 like
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Synonyms gene name
- cell division cycle associated 7-like
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Synonyms
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Locus
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Discovery year2005-05-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1B
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCTD nuclear envelope phosphatase 1 regulatory subunit 1
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Synonyms gene
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Synonyms gene name
- chromosome 16 open reading frame 69
- transmembrane protein 188
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-04-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelymphotoxin beta receptor
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-03-12
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-X-C motif chemokine ligand 11
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Synonyms gene
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Synonyms gene name
- small inducible cytokine subfamily B (Cys-X-Cys), member 11
- chemokine (C-X-C motif) ligand 11
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-06-23
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Entrez gene record
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Pubmed identfication
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Classification
- Chemokine ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namepatatin like phospholipase domain containing 7
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Synonyms gene
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Synonyms gene name
- chromosome 9 open reading frame 111
- patatin-like phospholipase domain containing 7
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-03-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Patatin like phospholipase domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprostate cancer associated transcript 6
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Synonyms gene
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Synonyms gene name
- KDM5B antisense RNA 1 (head to head)
- prostate cancer associated transcript 6 (non-protein coding)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2012-02-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Long non-coding RNAs with non-systematic symbols
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VEGA ID
MeSH Data
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Name
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ConceptScope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data