SMAD3 Inhibtor, SIS 3-d3
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Catalog numberS564502
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PricePlease ask
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Size1 mg
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Chemical available in other sizesPlease inquire size and price
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Stock availabilityPlease Inquire
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Cas number1512629-88-7
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Chemical s molecular weight456.55
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Chemical s main applicationsSMAD3 Inhibtor, SIS 3-d3 is the labeled analogue of SMAD3 Inhibtor, SIS 3 (S564500), which selectively inhibits TGF-β and activin. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts.
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Chemical s categoryAmines, Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
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Other name1-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3-(1-methyl-d3-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-propen-1-one
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Chemical s formulaC28H24D3N3O3
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Physical propertiesNo Data Available
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Melting temperatureNo Data Available
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Boiling temperatureNo Data Available
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Chemical s soluble inNo Data Available
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Stability conditionsNo Data Available
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StorageNo Data Available
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Gene target
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Gene symbolPDGFB, SMAD3
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Short nameSMAD3 Inhibtor, SIS 3-d3
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Alternative nameSMAD family member 3 Inhibtor, SIS 3-d3
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Alternative to gene targetSMAD family member 3, HSPC193 and HsT17436 and JV15-2 and LDS1C and LDS3 and MADH3, SMAD3 and IDBG-18366 and ENSG00000166949 and 4088, transforming growth factor beta receptor, nuclei, Smad3 and IDBG-175693 and ENSMUSG00000032402 and 17127, SMAD3 and IDBG-645466 and ENSBTAG00000012599 and 515125
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Gene info
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Identity
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Gene
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Long gene nameplatelet derived growth factor subunit B
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Synonyms gene
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Synonyms gene name
- platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
- platelet-derived growth factor beta polypeptide
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSMAD family member 3
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Synonyms gene
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Synonyms gene name
- MAD, mothers against decapentaplegic homolog 3 (Drosophila)
- SMAD, mothers against DPP homolog 3 (Drosophila)
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-11-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SMAD family
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VEGA ID
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Locus Specific Databases