SMAD3 Inhibtor, SIS 3

• Catalog number
  S564500
• Price
  Please ask
• Size
  2,5 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  Please Inquire
• Cas number
  1009104-85-1
• Chemical s molecular weight
  453.53
• Chemical s main applications
  SMAD3 Inhibitor, SIS3 selectively inhibits TGF-β and activin. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts.
• Chemical s category
  Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
• Other name
  1-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-propen-1-one
• Chemical s formula
  C28H27N3O3
• Physical properties
  No Data Available
• Melting temperature
  No Data Available
• Boiling temperature
  No Data Available
• Chemical s soluble in
  No Data Available
• Stability conditions
  No Data Available
• Storage
  No Data Available
• Chemical s specifications

• Gene target
  SMAD3   Inhibtor   SIS  
• Gene symbol
  PDGFB, SMAD3
• Short name
  SMAD3 Inhibtor, SIS 3
• Alternative name
  SMAD family member 3 Inhibtor, SIS 3
• Alternative to gene target
  SMAD family member 3, HSPC193 and HsT17436 and JV15-2 and LDS1C and LDS3 and MADH3, SMAD3 and IDBG-18366 and ENSG00000166949 and 4088, transforming growth factor beta receptor, nuclei, Smad3 and IDBG-175693 and ENSMUSG00000032402 and 17127, SMAD3 and IDBG-645466 and ENSBTAG00000012599 and 515125

Gene info

• Identity
  HGNC:8800
• Gene
  PDGFB
• Long gene name
  platelet derived growth factor subunit B
• Synonyms gene
  • SIS
• Synonyms gene name
  • platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
  • platelet-derived growth factor beta polypeptide
• Synonyms
  • SSV
• Synonyms name
  • oncogene SIS
  • becaplermin
• Locus
  22q13.1
• Discovery year
  2001-06-22
• Entrez gene record
  5155
• Pubmed identfication
  • 2991848
  • 1661670
• RefSeq identity
  • NM_002608
• VEGA ID
  OTTHUMG00000151029

Gene info

• Identity
  HGNC:6769
• Gene
  SMAD3
• Long gene name
  SMAD family member 3
• Synonyms gene
  • MADH3
• Synonyms gene name
  • MAD, mothers against decapentaplegic homolog 3 (Drosophila)
  • SMAD, mothers against DPP homolog 3 (Drosophila)
• Synonyms
  • JV15-2
  • HsT17436
• GenBank acession
  • BC050743
• Locus
  15q22.33
• Discovery year
  1996-11-15
• Entrez gene record
  4088
• Pubmed identfication
  • 8774881
  • 8673135
• RefSeq identity
  • NM_005902
• Classification
  • SMAD family
• VEGA ID
  OTTHUMG00000133230
• Locus Specific Databases
  • The Globin Gene Server

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