BX-471

• Catalog number
  B2407-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  (2R)-1-[[2-[(Aminocarbonyl)amino]-4-chlorophenoxy]acetyl]-4-[(4-fluorophenyl)methyl]-2-methylpiperazine, ZK-811752
• Description
  BX-471 is a potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM; displays 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
• CAS Number
  217645-70-0
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₁H₂₄ClFN₄O₃
• Molecular Weight
  434.89
• Cell Permeable
  True
• Purity
  ≥98% by HPLC
• Solubilities
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  A potent and selective CCR1 antagonist
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  512282
• PubChem CID Link
• SMILES
  CC1CN(CCN1C(=O)COC2=C(C=C(C=C2)Cl)NC(=O)N)CC3=CC=C(C=C3)F
• InChi
  InChI=1S/C21H24ClFN4O3/c1-14-11-26(12-15-2-5-17(23)6-3-15)8-9-27(14)20(28)13-30-19-7-4-16(22)10-18(19)25-21(24)29/h2-7,10,14H,8-9,11-13H2,1H3,(H3,24,25,29)/t14-/m1/s1
• InChi Key
  XQYASZNUFDVMFH-CQSZACIVSA-N
• Data Sheet Link
• MSDS Available
  True

• Gene target
  BX-471  
• Short name
  BX-471
• Alternative name
  BX-471

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