MCP-2, murine recombinant

Synonyms

Monocyte Chemotactic Protein-2, CCL8, HC14
Alternative_names

Monocyte Chemotactic Protein-2, CCL8, HC14, Small-inducible cytokine A8
Description

Chemoattractant for monocytes
Recombinant

Yes
Source

E. coli
Purity by SDS PAGE

≥98%
Assay

SDS-PAGE
Purity

≥98%
Biological activity

Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10-100 ng/ml.
Results

10-100 ng/ml.
Molecular Weight

8.5 kDa
Storage Temp

-20°C
Shipping

Gel pack
Shelf Life

12 months
Appearance

Lyophilized protein
Physical form description

Sterile filtered and then lyophilized with no additives
Reconstitution Instructions

Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.
Background Information

Macrophage/monocyte chemotactic protein-2 (MCP-2) plays an important role in the inflammatory response of blood monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. Recombinant murine MCP-2 is an 8.5 kDa protein containing 74 amino acid residues.
Handling

Centrifuge the vial prior to opening.
Usage

For Research Use Only! Not to be used in humans
Datasheet
Additional source

Recombinants or rec. proteins
Group

recombinants

Gene target

MCP-2 murine
Gene symbol

CCL8, CAPG, CCR2, SLC25A33, CCL2, CD46, CCL7, CCL13, MIR7-2, MIR329-2
Short name

MCP-2, murine recombinant
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Alternative name

MCP-2, murine Rec.
Alternative technique

rec

Identity

HGNC:10635
Gene

CCL8
Long gene name

C-C motif chemokine ligand 8
Synonyms gene
- SCYA8
Synonyms gene name
- small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)
- chemokine (C-C motif) ligand 8
Synonyms
- MCP-2
- HC14
GenBank acession
- X99886
Locus

17q12
Discovery year

1996-11-14
Entrez gene record

6355
Pubmed identfication
- 9119400
RefSeq identity
- NM_005623
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000132883

Identity

HGNC:29681
Gene

SLC25A33
Long gene name

solute carrier family 25 member 33
Synonyms gene name
- solute carrier family 25, member 33
- solute carrier family 25 (pyrimidine nucleotide carrier), member 33
Synonyms
- MGC4399
- BMSC-MCP
- PNC1
GenBank acession
- AF495714
Locus

1p36.22
Discovery year

2006-09-21
Entrez gene record

84275
Pubmed identfication
- 14715278
- 16949250
RefSeq identity
- NM_032315
Classification
- Solute carriers
VEGA ID

OTTHUMG00000001322

Identity

HGNC:10618
Gene

CCL2
Long gene name

C-C motif chemokine ligand 2
Synonyms gene
- SCYA2
Synonyms gene name
- small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
- chemokine (C-C motif) ligand 2
Synonyms
- MCP1
- MCP-1
- MCAF
- SMC-CF
- GDCF-2
- HC11
- MGC9434
Synonyms name
GenBank acession
- BC009716
Locus

17q12
Discovery year

1990-07-05
Entrez gene record

6347
Pubmed identfication
- 2004761
RefSeq identity
- NM_002982
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000132887

Identity

HGNC:6953
Gene

CD46
Long gene name

CD46 molecule
Synonyms gene
- MIC10
- MCP
Synonyms gene name
- antigen identified by monoclonal antibody TRA-2-10
- membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)
- CD46 antigen, complement regulatory protein
- CD46 molecule, complement regulatory protein
Synonyms
- TRA2.10
- MGC26544
- TLX
GenBank acession
- BC030594
Locus

1q32.2
Discovery year

1988-08-31
Entrez gene record

4179
Pubmed identfication
- 7929741
RefSeq identity
- NM_172361
Classification
- Sushi domain containing
- Complement system regulators and receptors
- CD molecules
VEGA ID

OTTHUMG00000036397
Locus Specific Databases
- LRG_155

Identity

HGNC:10634
Gene

CCL7
Long gene name

C-C motif chemokine ligand 7
Synonyms gene
- SCYA6
- SCYA7
Synonyms gene name
- small inducible cytokine A7 (monocyte chemotactic protein 3)
- chemokine (C-C motif) ligand 7
Synonyms
- MCP-3
- NC28
- FIC
- MARC
- MCP3
Synonyms name
- monocyte chemoattractant protein 3
- monocyte chemotactic protein 3
GenBank acession
- AF043338
Locus

17q12
Discovery year

1993-11-04
Entrez gene record

6354
Pubmed identfication
- 8461011
RefSeq identity
- NM_006273
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000132889

Identity

HGNC:10611
Gene

CCL13
Long gene name

C-C motif chemokine ligand 13
Synonyms gene
- SCYA13
Synonyms gene name
- small inducible cytokine subfamily A (Cys-Cys), member 13
- chemokine (C-C motif) ligand 13
Synonyms
- MCP-4
- NCC-1
- SCYL1
- CKb10
- MGC17134
GenBank acession
- AJ001634
Locus

17q12
Discovery year

1997-02-11
Entrez gene record

6357
Pubmed identfication
- 8661057
RefSeq identity
- NM_005408
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000132890

Name

Urine Specimen Collection
Concept

Scope note: Methods or procedures used to obtain samples of URINE.
Tree numbers
- E01.370.225.998.762
- E05.200.998.762
Qualifiers

ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data