Cyclin D1 Antibody
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Catalog numberGEN438202
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PricePlease ask
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Size100ug
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Also known asCyclin D1
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Other namesG1/S-specific cyclin-D1; G1/S-specific cyclin-D1; G1/S-specific cyclin-D1; BCL-1 oncogene; PRAD1 oncogene; B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; cyclin D1; B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogene
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameCCND1
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Gene name synonimsN/A
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Other gene namesCCND1; CCND1; BCL1; PRAD1; U21B31; D11S287E; BCL1; PRAD1; BCL-1
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG2a, kappa
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CloneDCS-6
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens), Monkey, Mouse (Mus musculus), Rat (Rattus norvegicus).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearanceN/A
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ConcentrationN/A
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Storage and shippingStore the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
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Tested applicationsELISA, Biological Function Blockade, Flow Cytometry, Immunofluorescence, Western Blot, Immunoprecipitation, Immunohistology
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCCND1, CCNDBP1
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Short nameCyclin D1 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameAnti-Cyclin D1
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namecyclin D1
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Synonyms gene
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Synonyms gene name
- cyclin D1 (PRAD1: parathyroid adenomatosis 1)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-06-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Cyclins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecyclin D1 binding protein 1
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Synonyms gene name
- cyclin D-type binding-protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-10-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data