PTPN11 (Tyr584) (Tyrosine-protein Phosphatase Non-receptor Type 11, Protein-tyrosine Phosphatase 2C, PTP-2C, Protein-tyrosine Phosphatase 1D, PTP-1D, SH-PTP3, SH-PTP2, SHP-2, Shp2, SHPTP2, PTP2C)

• Catalog number
  MBS627522
• Price
  Please ask
• Size
  0.2 mL

• Products_type
  Antibody
• Products_short_name
  [PTPN11]
• Products_name_syn
  [Anti -PTPN11 (Tyr584) (Tyrosine-protein Phosphatase Non-receptor Type 11, Protein-tyrosine Phosphatase 2C, PTP-2C, Protein-tyrosine Phosphatase 1D, PTP-1D, SH-PTP3, SH-PTP2, SHP-2, Shp2, SHPTP2, PTP2C)]
• Other_names
  [PTPN11 protein; PTPN11 protein; tyrosine-protein phosphatase non-receptor type 11; PTP-2C; OTTHUMP00000166107; OTTHUMP00000166108; protein tyrosine phosphatase-2; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; protein tyrosine phosphatase, non-receptor type 11]
• Other_gene_names
  [PTPN11; PTPN11; CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3; MGC14433]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Recognizes human SHP2.
• Purity
  Affinity Purified Purified by Protein A affinity chromatography.
• Form
  Supplied as a liquid in PBS, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB)
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  PTPN11   Tyr584   Tyrosine-protein   Phosphatase   Non-receptor   Protein-tyrosine   Phosphatase   PTP-2C   Protein-tyrosine   Phosphatase   PTP-1D   SH-PTP3   SH-PTP2   SHP-2   Shp2   SHPTP2   PTP2C  
• Gene symbol
  PTPN11, PTPN13, PTPN6, PTPRK, PTPRO, PTPRR, PTPRU, ACP1, REG1A, PTPN7
• Short name
  PTPN11 (Tyr584) (Tyrosine-protein Phosphatase Non-receptor 11, Protein-tyrosine Phosphatase 2C, PTP-2C, Protein-tyrosine Phosphatase 1D, PTP-1D, SH-PTP3, SH-PTP2, SHP-2, Shp2, SHPTP2, PTP2C)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  PTPN11 (Tyr584) (Tyrosine-protein Phosphatase Non-receptor classification 11, Protein-tyrosine Phosphatase 2C, PTP-2C, Protein-tyrosine Phosphatase 1D, PTP-1D, SH-PTP3, SH-PTP2, SHP-2, Shp2, SHPTP2, PTP2C)

Gene info

• Identity
  HGNC:9644
• Gene
  PTPN11
• Long gene name
  protein tyrosine phosphatase non-receptor type 11
• Synonyms gene
  • NS1
• Synonyms gene name
  • Noonan syndrome 1
  • protein tyrosine phosphatase, non-receptor type 11
• Synonyms
  • BPTP3
  • SH-PTP2
  • SHP-2
  • PTP2C
  • SHP2
• Synonyms name
  • SH2 domain-containing protein tyrosine phosphatase 2
• GenBank acession
  • D13540
• Locus
  12q24.13
• Discovery year
  1993-03-03
• Entrez gene record
  5781
• Pubmed identfication
  • 7894486
  • 1280823
• Classification
  • Protein tyrosine phosphatases non-receptor type
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000134334
• Locus Specific Databases
  • LRG_614

Gene info

• Identity
  HGNC:9646
• Gene
  PTPN13
• Long gene name
  protein tyrosine phosphatase non-receptor type 13
• Synonyms gene name
  • protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
• Synonyms
  • PTP1E
  • PTP-BAS
  • PTPL1
  • PTP-BL
• Synonyms name
  • APO-1/CD95 (Fas)-associated phosphatase
• Locus
  4q21.3
• Discovery year
  1995-02-17
• Pubmed identfication
  • 8287977
• Classification
  • Protein tyrosine phosphatases non-receptor type
  • PDZ domain containing
  • FERM domain containing
• VEGA ID
  OTTHUMG00000160968

Gene info

• Identity
  HGNC:9658
• Gene
  PTPN6
• Long gene name
  protein tyrosine phosphatase non-receptor type 6
• Synonyms
  • HCP
  • HCPH
  • PTP-1C
  • SHP-1
  • SHP1
• Locus
  12p13.31
• Discovery year
  1992-02-12
• Entrez gene record
  5777
• Pubmed identfication
  • 1639416
• RefSeq identity
  • NM_002831
• Classification
  • Protein tyrosine phosphatases non-receptor type
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000168518

Gene info

• Identity
  HGNC:9674
• Gene
  PTPRK
• Long gene name
  protein tyrosine phosphatase receptor type K
• Synonyms
  • R-PTP-kappa
• GenBank acession
  • L77886
• Locus
  6q22.33
• Discovery year
  1998-02-09
• Entrez gene record
  5796
• Pubmed identfication
  • 9047348
  • 8663237
• Classification
  • Protein tyrosine phosphatases receptor type
  • Fibronectin type III domain containing
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000015536

Gene info

• Identity
  HGNC:9678
• Gene
  PTPRO
• Long gene name
  protein tyrosine phosphatase receptor type O
• Synonyms
  • PTPU2
  • GLEPP1
  • PTP-U2
  • PTP-oc
  • NPHS6
• Synonyms name
  • osteoclastic transmembrane protein-tyrosine phosphatase
• GenBank acession
  • U20489
• Locus
  12p12.3
• Discovery year
  1995-02-22
• Entrez gene record
  5800
• Pubmed identfication
  • 7519601
  • 7665166
  • 21722858
• Classification
  • Protein tyrosine phosphatases receptor type
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000168786

Gene info

• Identity
  HGNC:9680
• Gene
  PTPRR
• Long gene name
  protein tyrosine phosphatase receptor type R
• Synonyms gene
  • PTPRQ
• Synonyms
  • PTPBR7
  • PTP-SL
  • EC-PTP
  • PCPTP1
• GenBank acession
  • D64053
• Locus
  12q15
• Discovery year
  1999-10-28
• Entrez gene record
  5801
• Pubmed identfication
  • 7557444
  • 10393441
• RefSeq identity
  • NM_002849
• Classification
  • Protein tyrosine phosphatases receptor type
• VEGA ID
  OTTHUMG00000169502

Gene info

• Identity
  HGNC:9683
• Gene
  PTPRU
• Long gene name
  protein tyrosine phosphatase receptor type U
• Synonyms
  • PTPRO
  • hPTP-J
  • PCP-2
  • FMI
  • PTP
• Synonyms name
  • pi R-PTP-Psi
• GenBank acession
  • U71075
• Locus
  1p35.3
• Discovery year
  1999-10-28
• Entrez gene record
  10076
• Pubmed identfication
  • 8700514
  • 9434160
• Classification
  • Protein tyrosine phosphatases receptor type
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000003699

Gene info

• Identity
  HGNC:122
• Gene
  ACP1
• Long gene name
  acid phosphatase 1
• Synonyms gene name
  • acid phosphatase 1, soluble
• Synonyms
  • HAAP
  • LMW-PTP
  • LMWPTP
• Synonyms name
  • acid phosphatase of erythrocyte
  • low molecular weight phosphotyrosine protein phosphatase
  • red cell acid phosphatase
• GenBank acession
  • M87546
• Locus
  2p25.3
• Discovery year
  1986-01-01
• Entrez gene record
  52
• Pubmed identfication
  • 457131
  • 1587862
  • 8586411
• RefSeq identity
  • NM_004300
• Classification
  • Acid phosphatases
  • Class II Cys-based phosphatases
• VEGA ID
  OTTHUMG00000086933

Gene info

• Identity
  HGNC:9951
• Gene
  REG1A
• Long gene name
  regenerating family member 1 alpha
• Synonyms gene
  • REG
• Synonyms gene name
  • regenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic thread protein)
• Synonyms
  • PSP
  • PTP
  • PSPS
  • PSPS1
• Synonyms name
  • pancreatic stone protein
  • pancreatic thread protein
• Locus
  2p12
• Discovery year
  1992-06-05
• Entrez gene record
  5967
• Pubmed identfication
  • 2332435
  • 8333731
• RefSeq identity
  • NM_002909
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000130016

Gene info

• Identity
  HGNC:9659
• Gene
  PTPN7
• Long gene name
  protein tyrosine phosphatase non-receptor type 7
• Synonyms
  • HEPTP
  • LC-PTP
• GenBank acession
  • BC001746
• Locus
  1q32.1
• Discovery year
  1993-03-03
• Entrez gene record
  5778
• Pubmed identfication
  • 1510684
• RefSeq identity
  • NM_002832
• Classification
  • Protein tyrosine phosphatases non-receptor type
• VEGA ID
  OTTHUMG00000035931

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