Recombinant Human CD32b / FCGR2B Protein (His tag)
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Catalog number
PKSH031726-50µg
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Price
Please ask
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Size
50µg
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Synonym
CD32;CD32B;Fc gamma RIIB;FCGR2
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Activity
Measured by its binding ability in a functional ELISA. Immobilized recombinant human CD32b at 10 μg/ml (100 μl/well) can bind human IgG2 with a linear range of 0.16-6.4 μg/ml.
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Sequence
Ala 46-Pro 217
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Fusion tag
C-His
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Accession
NP_001002274.1
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Expressed Host
HEK293 Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
> 95 % as determined by SDS-PAGE
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Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
20.8 kDa
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AP Mol Mass
25-30 kDa
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Formulation
Lyophilized from sterile PBS, pH 7.4
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Background
Processing of the N-terminal initiator methionine or formylated methionine is an essential cellular process conserved from prokaryotes to eukaryotes. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. As a member of the M24 family of metalloproteases, METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents.
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Conjugation
histidine
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
FCGR2B
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Short name
Recombinant CD32b / FCGR2B Protein (His tag)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Label
His
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Species
Human, Humans
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Alternative name
Rec. H. sapiens CD32b / fragment c fragment on Immunoglobulin G, low affinity IIb, receptor (CD32) Protein (histidine detection labelled)
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Alternative technique
rec
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Alternative to gene target
Fc fragment of IgG, low affinity IIb, receptor (CD32), CD32 and CD32B and FCG2 and FCGR2 and IGFR2, FCGR2B and IDBG-104308 and ENSG00000072694 and 2213, IgG binding, Plasma membranes
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Gene info
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Identity
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Gene
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Long gene name
Fc gamma receptor IIb
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Synonyms gene
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Synonyms gene name
- Fc fragment of IgG, low affinity IIb, receptor for (CD32)
- Fc fragment of IgG, low affinity IIb, receptor (CD32)
- Fc fragment of IgG receptor IIb
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Synonyms
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GenBank acession
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Locus
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Discovery year
1991-08-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Immunoglobulin like domain containing
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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