ERCC8 shRNA Plasmid (Human)

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Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Kit

Plasmid mini made and maxi DNA purification kits can be silica gel or anion exchange, endotoxin free and are used to produce pure plasmids that are small DNA molecules within a cell separated from chromosomal DNA and can replicate independently. They are most commonly found in bacteria as small circular, double-stranded DNA molecules; however, plasmids are sometimes present in archaea and eukaryotic organisms. In nature, plasmids often carry genes that may benefit the survival of the organism, for example antibiotic resistance. While the chromosomes are big and contain all the essential information for living, plasmids usually are very small and contain only additional information. Artificial plasmids are widely used as vectors in molecular cloning, serving to drive the replication of recombinant DNA sequences within host organisms.

Gene target

ERCC8 shRNA
Gene symbol

ERCC8-AS1, ERCC8
Short name

ERCC8 shRNA Plasmid ( )
Technique

plasmid, plasmids in 1
Species

Human, Humans
Alternative name

excision repair cross-complementing rodent repair deficiency, complementation family 8 short hairpin RNA Plasmid (H. sapiens)
Alternative technique

plasmids
Alternative to gene target

excision repair cross-complementing rodent repair deficiency, complementation group 8, CKN1 and CSA and UVSS2, ERCC8 and IDBG-22959 and ENSG00000049167 and 1161, protein complex binding, nuclei, Ercc8 and IDBG-181454 and ENSMUSG00000021694 and 71991, ERCC8 and IDBG-628902 and ENSBTAG00000021606 and 518857

Identity

HGNC:3439
Gene

ERCC8
Long gene name

ERCC excision repair 8, CSA ubiquitin ligase complex subunit
Synonyms gene
- CKN1
Synonyms gene name
- Cockayne syndrome 1 (classical)
- excision repair cross-complementing rodent repair deficiency, complementation group 8
- excision repair cross-complementation group 8
Synonyms
- CSA
GenBank acession
- U28413
Locus

5q12.1
Discovery year

1995-02-07
Entrez gene record

1161
Pubmed identfication
- 8596535
RefSeq identity
- NM_000082
Classification
- WD repeat domain containing
- ERCC excision repair associated
VEGA ID

OTTHUMG00000097741
Locus Specific Databases
- LRG_466