TLR4 Antibody

• Catalog number
  3251-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  TLR4
• Target Alternative Name
  ARMD10, CD284, TOLL, hToll, Toll-like receptor 4
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant human TLR4
• Accession
  O00206
• Gene Id
  7099
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.2 mg/ml
• Formulation
  100 µg (0.2 mg/ml) Protein A affinity purified rabbit anti-TLR4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot, Flow cytometry
• Application And Usages
  Western blot analysis (0.5-4 µg/ml). The antibody is also suitable for flow cytometric analysis of cell surface expression of TLR4. However, the optimal conditions should be determined individually.
• Description
  TLR4 (Toll-like receptor 4) is a mammalain homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TLR4  
• Gene symbol
  TLR4
• Short name
  TLR4 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  toll-like receptor 4 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  toll-like receptor 4, ARMD10 and CD284 and TLR-4 and TOLL, TLR4 and IDBG-82738 and ENSG00000136869 and 7099, protein binding, Cell surfaces, Tlr4 and IDBG-156729 and ENSMUSG00000039005 and 21898, TLR4 and IDBG-638758 and ENSBTAG00000006240 and 281536

Gene info

• Identity
  HGNC:11850
• Gene
  TLR4
• Long gene name
  toll like receptor 4
• Synonyms gene name
  • toll-like receptor 4
• Synonyms
  • hToll
  • CD284
  • TLR-4
  • ARMD10
• GenBank acession
  • U88880
• Locus
  9q33.1
• Discovery year
  1998-06-25
• Entrez gene record
  7099
• Pubmed identfication
  • 9435236
  • 9237759
• RefSeq identity
  • NM_138554
• Classification
  • Toll like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000021046
• Locus Specific Databases
  • LRG_320

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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