AGT Antibody (CT)
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Catalog number6708-100
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PricePlease ask
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Size100 μl
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Antibody TargetAGT
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Target Alternative NameAGT; SERPINA8; Angiotensinogen; Serpin A8; Angiotensin-1; Angiotensin I; Angiotensin-2; Angiotensin II; Angiotensin-3; Angiotensin III;
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Antibody TypePolyclonal
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Species ReactivitiesHuman
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Immunogen SequenceThis AGT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418-450 amino acids from the C-terminal region of human AGT.
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AccessionP01019
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Gene IdAGT
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AppearanceColorless liquid
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FormLiquid
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Formulation100 µl of antibody in PBS with 0.09% (W/V) sodium azide
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PurificationThis antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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ApplicationWestern blot, IHC
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Positive ControlWestern blot: HepG2 cell lysate, IHC: human hepatocarcinoma tissue
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Application And UsagesWestern blot: ~1:1000, IHC: ~1:10-1:50
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DescriptionAngiotensinogen, also known as AGT and SERPINA8, is a member of the serpin family. It is anα-2-globulinthat is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essential component of the renin-angiotensin system (RAS) and a potent regulator of blood pressure. It is expressed by the liver and secreted in plasma. Angiotensinogen is cleaved into three chains: Angiotensin-1 (Ang I), Angiotensin-2 (Ang II), and Angiotensin-3 (Ang III). Angiotensin-1 is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to yield the physiologically active peptide angiotensin-2. Angiotensin-1 and angiotensin-2 can be further processed to generate angiotensin-3, angiotensin-4. Angiotensin 1-7 is cleaved from angiotensin-2 by ACE2. Angiotensin-2 acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system. Defects in AGT are associated with susceptibility to essential hypertension and renal tubular dysgenesis (RTD).
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedVerified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolAGT, SLC7A13, AGXT, TRT-AGT3-1, TRT-AGT2-1, TRT-AGT2-2, TRT-AGT1-3, TRT-AGT7-1, TRT-AGT1-1, TRT-AGT1-2
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Short nameAGT Antibody (CT)
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameangiotensinogen (serpin peptidase inhibitor, clade A, member 8) (antibody to-) (CT)
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Alternative techniqueantibodies
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Alternative to gene targetangiotensinogen (serpin peptidase inhibitor, clade A, member 8), ANHU and SERPINA8, AGT and IDBG-107363 and ENSG00000135744 and 183, type 2 angiotensin receptor binding, Extracellular, Agt and IDBG-200169 and ENSMUSG00000031980 and 11606, AGT and IDBG-632058 and ENSBTAG00000012393 and 527114
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Gene info
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Identity
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Gene
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Long gene nameangiotensinogen
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Synonyms gene
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Synonyms gene name
- serpin peptidase inhibitor, clade A, member 8
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Synonyms name
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GenBank acession
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Neuropeptides
- Serpin peptidase inhibitors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesolute carrier family 7 member 13
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Synonyms gene name
- solute carrier family 7 (anionic amino acid transporter), member 13
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-09-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Solute carriers
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namealanine--glyoxylate and serine--pyruvate aminotransferase
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Synonyms gene
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Synonyms gene name
- serine:pyruvate aminotransferase
- alanine-glyoxylate aminotransferase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1990-11-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametrRNA-Thr (anticodon AGT) 3-1
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Synonyms gene
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Synonyms gene name
- transfer RNA threonine 21 (anticodon AGU)
- transfer RNA-Thr (AGT) 3-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Thr (anticodon AGT) 2-1
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Synonyms gene
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Synonyms gene name
- transfer RNA threonine 14 (anticodon AGU)
- transfer RNA-Thr (AGT) 2-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Thr (anticodon AGT) 2-2
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Synonyms gene
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Synonyms gene name
- transfer RNA threonine 15 (anticodon AGU)
- transfer RNA-Thr (AGT) 2-2
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Thr (anticodon AGT) 1-3
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Synonyms gene
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Synonyms gene name
- transfer RNA threonine 4 (anticodon AGU)
- transfer RNA-Thr (AGT) 1-3
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Thr (AGT) 7-1
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Synonyms gene
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Synonyms gene name
- tRNA threonine (AGU) 3
- transfer RNA threonine 3 (anticodon AGU)
- transfer RNA-Thr (AGT) 7-1
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-05-24
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Entrez gene record
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Pubmed identfication
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Classification
- Low confidence cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Thr (anticodon AGT) 1-1
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Synonyms gene
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Synonyms gene name
- transfer RNA threonine 8 (anticodon AGU)
- transfer RNA-Thr (AGT) 1-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Thr (anticodon AGT) 1-2
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Synonyms gene
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Synonyms gene name
- transfer RNA threonine 9 (anticodon AGU)
- transfer RNA-Thr (AGT) 1-2
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
