PE-Linked Polyclonal Antibody to ATP Dependent DNA ligase I (LIG1)

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Properties

If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Group

Polyclonals and antibodies
About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
French translation

anticorps

Gene target

PE-Linked ATP Dependent DNA ligase LIG1
Gene symbol

ETV3, ERF, LIG1, VPS9D1, LRIG1, PRKDC, NFATC2, HLA-DOA
Short name

PE-Linked Polyclonal Antibody ATP Dependent DNA ligase I (LIG1)
Technique

Polyclonal, Antibody, dna, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
Label

PE
Alternative name

peroxidase-Linked polyclonal (antibody to-) to adenosine triphosphate Dependent Desoxyribonucleic acid ligase I (LIG1)
Alternative technique

polyclonals, antibodies

Identity

HGNC:3492
Gene

ETV3
Long gene name

ETS variant transcription factor 3
Synonyms gene name
- ets variant gene 3, ETS family transcriptional repressor
- ETS variant 3
Synonyms
- PE-1
GenBank acession
- BC022868
Locus

1q23.1
Discovery year

1994-12-15
Entrez gene record

2117
Pubmed identfication
- 8020980
RefSeq identity
- NM_005240
Classification
- ETS transcription factor family
VEGA ID

OTTHUMG00000034298

Identity

HGNC:6598
Gene

LIG1
Long gene name

DNA ligase 1
Synonyms gene name
- ligase I, DNA, ATP-dependent
Synonyms name
- DNA ligase I
Locus

19q13.33
Discovery year

1991-05-09
Entrez gene record

3978
Pubmed identfication
- 1733856
RefSeq identity
- NM_000234
Classification
- Nucleotide excision repair
- DNA ligases
VEGA ID

OTTHUMG00000183187
Locus Specific Databases
- LIG1base: Mutation registry for DNA ligase I deficiency
- LRG_78

Identity

HGNC:17360
Gene

LRIG1
Long gene name

leucine rich repeats and immunoglobulin like domains 1
Synonyms
- LIG-1
- DKFZP586O1624
- LIG1
Synonyms name
- ortholog of mouse integral membrane glycoprotein LIG-1
- leucine-rich repeat protein LRIG1
GenBank acession
- AB050468
Locus

3p14.1
Discovery year

2002-08-23
Entrez gene record

26018
Pubmed identfication
- 11414704
- 12234026
RefSeq identity
- NM_015541
Classification
- I-set domain containing
VEGA ID

OTTHUMG00000158727

Identity

HGNC:7776
Gene

NFATC2
Long gene name

nuclear factor of activated T cells 2
Synonyms gene name
- nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
- nuclear factor of activated T-cells 2
Synonyms
- NF-ATP
- NFATp
- NFAT1
GenBank acession
- U43342
- U43341
Locus

20q13.2
Discovery year

1994-11-16
Entrez gene record

4773
Pubmed identfication
- 8202141
RefSeq identity
- NM_012340
Classification
- IPT domain containing
- Nuclear factors of activated T-cells
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000032747

Name

Ligase Chain Reaction
Concept

Scope note: A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
Tree numbers
- E05.393.620.311
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data