Recombinant Mouse CD147 / EMMPRIN / Basigin Protein (His & Fc tag) 100µg

• Catalog number
  PKSM040728-100µg
• Price
  Please ask
• Size
  100µg

• Activity
  Using the Octet RED System, the affinity constant (Kd) of mouse CD147-Fc bound to Human PPIA-His was 0.4 μM.
• Synonym
  AI115436;AI325119;CD147;EMMPRIN;HT-7
• Sequence
  Met 1-Arg 209
• Fusion tag
  C-His & Fc
• Accession
  NP_001070652.1
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 90 % as determined by SDS-PAGE
• Endotoxin
  < 1.0 EU per μg of the protein as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  48.6 kDa
• AP Mol Mass
  60-70 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.
• Technical data
• Conjugation
  histidine
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CD147   EMMPRIN   Basigin   Protein   His   tag   100µg  
• Gene symbol
  BSG
• Short name
  Recombinant Mouse CD147 / EMMPRIN / Basigin Protein (His & Fc tag) 100µg
• Technique
  Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  mouse
• Label
  His
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse CD147 / EMMPRIN / Basigin Protein (histidine & fragment c detection labelled) 100µg
• Alternative technique
  rec, murine

Gene info

• Identity
  HGNC:1116
• Gene
  BSG
• Long gene name
  basigin (Ok blood group)
• Synonyms gene
  • OK
• Synonyms gene name
  • basigin
• Synonyms
  • EMMPRIN
  • CD147
  • EMPRIN
• Synonyms name
  • Ok blood group
  • extracellular matrix metalloproteinase inducer
  • Tumor cell-derived collagenase stimulatory factor
• GenBank acession
  • L10240
• Locus
  19p13.3
• Discovery year
  1993-10-25
• Entrez gene record
  682
• Pubmed identfication
  • 8404035
  • 7812975
• RefSeq identity
  • NM_001728
• Classification
  • Basigin family
  • I-set domain containing
  • Blood group antigens
  • CD molecules
• VEGA ID
  OTTHUMG00000177718
• Locus Specific Databases
  • Blood Group Antigen Mutation Database
  • LRG_816

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products