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Products_type
Antibody
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Products_short_name
[Basigin / Emmprin / CD147]
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Products_name_syn
[Anti-Basigin / Emmprin / CD147 Antibody (clone MEM-M6/2) IHC-plus; BSG; 5F7; Basigin; Basigin (Ok blood group); CD147 antigen; Collagenase stimulatory factor; EMMPRIN; OK; OK blood group antigen; TCSF; CD147; M6; Emmprin; Human Basigin; Emmprin; CD147]
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Other_names
[basigin isoform 1; Basigin; basigin; CD147 antigen; OK blood group antigen; collagenase stimulatory factor; leukocyte activation antigen M6; extracellular matrix metalloproteinase inducer; tumor cell-derived collagenase stimulatory factor; basigin (Ok blood group); 5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD_antigen: CD147]
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Products_gene_name
[BSG]
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Products_gene_name_syn
[CD147]
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Other_gene_names
[BSG; BSG; M6; OK; 5F7; TCSF; CD147; EMMPRIN; EMMPRIN; TCSF]
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Clonality
Monoclonal
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Clone
[MEM-M6/2]
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Reactivity
Human, Porcine
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Specificity
The antibody MEM-M6/2 recognizes extracellular Ig domain D1 of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes. The antibody MEM-M6/1 is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
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Purity
Purified by protein-A affinity chromatography. Greater than 95% by SDS-PAGE.
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Form
PBS, 15 mM sodium azide, approx., pH 7.4.
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Concentration
1 mg/ml
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Storage_stability
Store at 2°C to 8°C. Do not freeze.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Flow Cytometry (FC/FACS)
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus